Evidence map›Paper›PMID 40332402›Full record

ArticleInternational journal of molecular sciences2025

Metabolites Isolated from

Javier Palacios, Carlos Villarroel, Daniel Asunción-Alvarez, Fredi Cifuentes, Adrián Paredes, Chukwuemeka R Nwokocha, Alejandro Castro-Álvarez, Claudio Parra

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Javier PalaciosLaboratorio de Bioquímica Aplicada, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique 1110939, Chile.ORCID 0000-0002-7997-9295
Carlos VillarroelLaboratorio de Bioquímica Aplicada, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique 1110939, Chile.
Daniel Asunción-AlvarezLaboratorio de Bioquímica Aplicada, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique 1110939, Chile.ORCID 0000-0001-7498-2121
Fredi CifuentesLaboratorio de Fisiología Experimental, Instituto Antofagasta, Universidad de Antofagasta, Antofagasta 1271155, Chile.ORCID 0000-0001-5922-8892
Adrián ParedesLaboratorio de Productos Naturales, Departamento de Química, Facultad de Ciencias Básicas, Universidad de Antofagasta, Antofagasta 1270300, Chile.ORCID 0000-0003-3332-8582
Chukwuemeka R NwokochaDepartment of Basic Medical Sciences Physiology Section, Faculty of Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica.ORCID 0000-0001-7092-9382
Alejandro Castro-ÁlvarezDepartamento de Ciencias Preclínicas, Facultad de Medicina, Universidad de La Frontera, Av. Francisco Salazar 01145, Temuco 4780000, Chile.ORCID 0000-0001-8360-8027
Claudio ParraDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Edmundo Larenas 129, Concepción 4070371, Chile.ORCID 0000-0001-7356-2782

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 11190972Fondo Nacional de Desarrollo Científico y Tecnológico 1200610Fondo Nacional de Desarrollo Científico y Tecnológico 1240262
6 · The paper itself

Abstract

Angiotensin-Converting Enzyme (ACE) plays a pivotal role in the renin-angiotensin system, modulating blood pressure and electrolyte homeostasis by deactivating bradykinin and activating angiotensin II. Metabolites from

Indexed as

Angiotensin-Converting Enzyme InhibitorsMuscle, Smooth, VascularOximesPeptidyl-Dipeptidase APlant ExtractsAnimalsMolecular Docking SimulationAngiotensin-Converting Enzyme InhibitorsOximesPeptidyl-Dipeptidase APlant Extractsacetophenonearterial hypertensionmedicinal plantsmolecular dockingoximesvascular response

Identifiers

PMID40332402
PMCPMC12027692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.