Evidence map›Paper›PMID 40332331›Full record

ArticleInternational journal of molecular sciences2025

Role of Liver Kinase 1B in Platelet Activation and Host Defense During

Osoul Chouchane, Valentine Léopold, Christine C A van Linge, Alex F de Vos, Joris J T H Roelofs, Cornelis van 't Veer, Tom van der Poll

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Osoul ChouchaneCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Valentine LéopoldCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-2131-5760
Christine C A van LingeCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0003-2787-8895
Alex F de VosCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-2472-3014
Joris J T H RoelofsDepartment of Pathology, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0001-9595-6571
Cornelis van 't VeerCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Tom van der PollCenter of Infection and Molecular Medicine, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Funding

Fondation Bettencourt SchuellerLandsteiner Foundation for Blood Transfusion Research 1901Servier (France)
6 · The paper itself

Abstract

Pneumonia is the most common cause of sepsis, with

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaePlatelet ActivationProtein Serine-Threonine KinasesSepsisAMP-Activated Protein KinasesAnimalsBlood PlateletsMiceMice, Inbred C57BLMice, KnockoutPlatelet Membrane GlycoproteinsAMP-Activated Protein KinasesPlatelet Membrane Glycoproteinsplatelet membrane glycoprotein VIProtein Serine-Threonine KinasesStk11 protein, mousemicrobes–host interactionmicrobial infectionmolecular and cell biology

Identifiers

PMID40332331
PMCPMC12028316

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.