Evidence map›Paper›PMID 40332314›Full record

ArticleInternational journal of molecular sciences2025

Complexity of Damage-Associated Molecular Pattern Molecule Expression Profile in Porcine Brain Affected by Ischemic Stroke.

Dominika Golubczyk, Aleksandra Mowinska, Piotr Holak, Piotr Walczak, Miroslaw Janowski, Izabela Malysz-Cymborska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dominika GolubczykTi-com LLC, Władysława Trylińskiego 2, 10-683 Olsztyn, Poland.ORCID 0000-0001-5692-6329
Aleksandra MowinskaDepartment of Neurology and Neurosurgery, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, Warszawska 30, 10-082 Olsztyn, Poland.ORCID 0000-0001-6789-2646
Piotr HolakDepartment of Surgery and Radiology with Clinic, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn, Poland.ORCID 0000-0002-2050-1959
Piotr WalczakProgram in Image Guided Neurointerventions, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, 670 W. Baltimore Street, Baltimore, MD 21201, USA.ORCID 0000-0002-3733-3322
Miroslaw JanowskiProgram in Image Guided Neurointerventions, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, 670 W. Baltimore Street, Baltimore, MD 21201, USA.ORCID 0000-0001-5261-7975
Izabela Malysz-CymborskaDepartment of Neurology and Neurosurgery, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, Warszawska 30, 10-082 Olsztyn, Poland.ORCID 0000-0003-4192-6726

Funding

Minister of Science under the Regional Initiative of Excellence ProgramNational Science Centre Poland UMO-2018/29/B/NZ5/00921
6 · The paper itself

Abstract

Studies using large animal models are essential for better understanding the molecular processes underlying neurological diseases, including ischemic stroke, and serve as a robust foundation for evaluating potential therapies. To better understand the complex role of damage-associated molecular pattern molecules (DAMPs) after ischemia, we aimed to determine their expression in the porcine brain affected by ischemic stroke at four time points: 6 h, 24 h, 3 days and 7 days post-stroke. Within the first 24 h after the stroke, we observed the increased expression of several key factors, including calcium-binding proteins, peroxiredoxins, heat shock proteins and interleukins (

Indexed as

AlarminsBrainBrain IschemiaIschemic StrokeAnimalsDisease Models, AnimalSwineVascular Endothelial Growth Factor AAlarminsVascular Endothelial Growth Factor Aanimal modelbrainDAMPspigstroke

Identifiers

PMID40332314
PMCPMC12027851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.