Evidence map›Paper›PMID 40332276›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2025

Comparison of myocardial perfusion scintigraphy and strain echocardiography in patients undergoing coronary angiography.

Çağlar Kaya, Muhammet Gürdoğan

Abstract readComparative Study
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Çağlar KayaTrakya University, Department of Cardiology - Edirne, Turkey.ORCID http://orcid.org/0000-0002-2968-5352
Muhammet GürdoğanTrakya University, Department of Cardiology - Edirne, Turkey.ORCID http://orcid.org/0000-0001-5650-9066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMyocardial perfusion scintigraphy is a common non-invasive method for assessing ischemic burden, though artifacts can affect accuracy. Speckle-tracking strain echocardiography improves left ventricular function assessment, and global longitudinal strain correlates well with coronary artery disease. The aim of this study was to compare myocardial perfusion scintigraphy with global longitudinal strain in stable angina pectoris patients.

methodsA total of 133 suspected coronary artery disease patients who underwent myocardial perfusion scintigraphy and coronary angiography were prospectively enrolled and classified as myocardial perfusion scintigraphy true positives or false positives based on coronary angiography results. Global longitudinal strain values for the epicardium, endocardium, and myocardium (avg) were calculated.

resultsIschemic percentages of myocardial perfusion scintigraphy>12% and mid-wall global longitudinal strain<-18.4% correlated with true positive coronary angiography results. Left ventricular ejection fraction/global longitudinal strain mid ratio positively correlated with coronary artery disease presence and severity. Higher ischemic percentages of myocardial perfusion scintigraphy showed a negative correlation (r: -0.2606, p: 0.002) with global longitudinal strain, indicating a greater likelihood of coronary artery disease (OR 0.25, 95%CI 0.08-0.73, p: 0.012). Female sex was linked to fewer true positive myocardial perfusion scintigraphy results.

conclusionThe GLS value of the Left Ventricle obtained by two-dimentional strain echocardiography offers sensitivity and specificity similar to myocardial perfusion scintigraphy in the detection of coronary artery disease.. An elevated left ventricular ejection fraction/global longitudinal strain ratio is a significant predictor of the presence and severity of coronary artery disease.

Indexed as

Coronary AngiographyCoronary Artery DiseaseEchocardiographyMyocardial Perfusion ImagingAgedFemaleHumansMaleMiddle AgedProspective StudiesSensitivity and SpecificityStroke Volume

Identifiers

PMID40332276
PMCPMC12051942

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