Evidence map›Paper›PMID 40332264›Full record

Trial reportRevista da Associacao Medica Brasileira (1992)2025

Is cesarean scar defect becoming history? The effect of uterotomy closure.

Neset Gumusburun, Ulya Uskent

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Neset GumusburunTokat Gaziosmanpasa University Hospital, Department of Obstetrics and Gynecology - Tokat, Türkiye.ORCID http://orcid.org/0000-0003-4746-5414
Ulya UskentGayrettepe Florence Nightingale Hospital, Department of Obstetrics and Gynecology - İstanbul, Türkiye.ORCID http://orcid.org/0000-0002-6618-6528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIsthmocele or cesarean scar defect is a pouch-like defect in the myometrium at the isthmic level that is thought that it might occur as a result of the insufficient healing process of the uterine incision after cesarean section. It is important not to underestimate isthmocele and its preventive measures since it might cause serious gynecologic and obstetric complications. However, the best suturing technique suitable for the prevention of isthmocele formation is yet to be identified. The aim of this study was to compare the effects of three different uterine closure techniques applied during cesarean section on isthmocele formation.

methodsIn this prospective study, a total of 120 term (>37 weeks) pregnant women with no history of cesarean section and scheduled for primary cesarean section were randomized preoperatively to three different uterotomy closure techniques (baseball, single-locked, and single-unlocked groups).

resultsIn a total of 43 patients, postoperative third-month sonography revealed isthmocele as an anechoic triangular area with ≥1 mm depth at the scar site. Compared with the single-locked and single-unlocked groups, isthmocele development was significantly lower in the baseball-type closure group (47.5% in the single-locked, 46.2% in the single-unlocked, and 15.4% in the baseball-type closure group). The group with the highest residual myometrial thickness, that is, 5.7 mm, was again the patients who underwent baseball sutures.

conclusionUterotomy closure with baseball-type suturing seems to be an advantageous method as compared to the traditional techniques in terms of preserving the residual myometrial thickness and preventing isthmocele formation.

Indexed as

Cesarean SectionCicatrixSuture TechniquesUterusAdultFemaleHumansMyometriumPostoperative ComplicationsPregnancyProspective StudiesTreatment OutcomeUltrasonographyWound Healing

Identifiers

PMID40332264
PMCPMC12051948

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.