Evidence map›Paper›PMID 40332252›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2025

Human papillomavirus vaccination: if the vaccine is important and available, why not use it?

Georgiana Sousa Freire, Carolina Lavacchini Ramunno Amaral, Juliana Jorge Romano, Camila Bussamra Aulicino, Cláudia Vaz de Melo Sette, Juliana Vieira Biason Bonometto, Jean Henri Maselli-Schoueri, Luiz Vinicius de Alcantara Sousa, Auro Del Giglio, Daniel de Iracema Gomes Cubero

Abstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Georgiana Sousa FreireCentro Universitário Faculdade de Medicina do ABC - Santo André (SP), Brazil.ORCID http://orcid.org/0009-0007-8817-3289
Carolina Lavacchini Ramunno AmaralCentro Universitário Faculdade de Medicina do ABC - Santo André (SP), Brazil.ORCID http://orcid.org/0009-0006-3568-2138
Juliana Jorge RomanoCentro Universitário Faculdade de Medicina do ABC - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0001-7978-6189
Camila Bussamra AulicinoCentro Universitário Faculdade de Medicina do ABC - Santo André (SP), Brazil.ORCID http://orcid.org/0009-0004-8863-5779
Cláudia Vaz de Melo SetteCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0001-6789-9039
Juliana Vieira Biason BonomettoCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0009-0002-1541-8859
Jean Henri Maselli-SchoueriCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0003-2509-3592
Luiz Vinicius de Alcantara SousaCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0002-6895-4914
Auro Del GiglioCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0002-2009-824X
Daniel de Iracema Gomes CuberoCentro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.ORCID http://orcid.org/0000-0002-1936-2605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman papillomavirus (HPV) is the most common virus of the reproductive tract, is linked to cervical cancer, and can be prevented by vaccination, which is most effective if the vaccine is administered before sexual activity begins.

methodsThis descriptive, cross-sectional, and qualitative study was based on a survey containing 15 questions delivered to schools in three cities in the ABC region. Two schools from high-income neighborhoods and two from low-income neighborhoods were selected in each city based on real estate values. Data were expressed in absolute numbers and percentages and interpreted by descriptive analysis. The statistical tests of association were performed.

resultsTwelve schools were invited and nine agreed to participate. Of the 4,503 questionnaires delivered, 1,921 were completed by parents and guardians. The vaccination rate was 56.05% in private schools and 66.58% in public schools. Private vs. public school was not an independent factor for vaccination, but residing in a low-income neighborhood and city was a determinant factor. Approximately 40% of the parents/guardians reported not having their children vaccinated, primarily due to concerns about adverse effects.

conclusionDespite being freely available and proven effective, the human papillomavirus vaccine remains underutilized. The reasons exposed in this paper may be useful in strategies to enhance vaccination coverage.

trial registrationThis study was approved by the research ethics committee under the number 2.143.196.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationAdolescentBrazilChildCross-Sectional StudiesFemaleHuman Papillomavirus VirusesHumansMaleParentsQualitative ResearchSchoolsSocioeconomic FactorsPapillomavirus Vaccines

Identifiers

PMID40332252
PMCPMC12051950

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.