Evidence map›Paper›PMID 40332224›Full record

ArticleInternational journal of molecular sciences2025

Uncovering a Novel Pathogenic Mechanism of

Valeria Capaci, Luisa Zupin, Martina Magistrati, Maria Teresa Bonati, Fulvio Celsi, Irene Marrone, Francesco Baldo, Blendi Ura, Beatrice Spedicati, Anna Morgan and 5 more

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. [Advances in the molecular genetics of nuclear gene mutations causing pediatric mitochondrial cardiomyopathy].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Valeria CapaciInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-0110-5942
Luisa ZupinInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0001-5886-9129
Martina MagistratiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0002-5864-5819
Maria Teresa BonatiInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0001-8024-0482
Fulvio CelsiInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-9760-8463
Irene MarroneDepartment of Life Science, University of Trieste, 34127 Trieste, Italy.
Francesco BaldoInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-7523-3154
Blendi UraInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.
Beatrice SpedicatiInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-7432-4708
Anna MorganInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0001-6290-445X
Irene BrunoInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.
Massimo ZevianiInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.
Cristina DallabonaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0003-4397-9143
Giorgia GirottoInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0003-4507-6589
Andrea MagnolatoInstitute for Maternal and Child Health IRCCS Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-5099-6526

Funding

European Union - Next Generation EU - Mission 4 CUP G53D23005010006 (grant number 2022A4CFKHItalian Ministry of Health, through the contribution given to the Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste - Italy RC 10/24; RC 13/24; RC 36/25; M-mito 5M19_5
6 · The paper itself

Abstract

The

Indexed as

ATPases Associated with Diverse Cellular ActivitiesElectron Transport Complex IIIHearing Loss, SensorineuralMitochondrial DiseasesChild, PreschoolFibroblastsHumansMitochondriaMutationPhenotypeATPases Associated with Diverse Cellular ActivitiesBCS1L protein, humanElectron Transport Complex IIIassembly chaperoneBCS1Lcomplex IIIelectron transfer chainmitochondrial disorder

Identifiers

PMID40332224
PMCPMC12027322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.