Evidence map›Paper›PMID 40332092›Full record

ArticleInternational journal of molecular sciences2025

GBLUP Outperforms Quantile Mapping and Outlier Detection for Enhanced Genomic Prediction.

Osval Antonio Montesinos-López, José Crossa, Paolo Vitale, Guillermo Gerard, Leonardo Crespo-Herrera, Susanne Dreisigacker, Carolina Saint Pierre, Luis G Posadas, Afolabi Agbona, Raymundo Buenrostro-Mariscal and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Osval Antonio Montesinos-LópezFacultad de Telemática, Universidad de Colima, Colima 28040, CL, Mexico.
José CrossaInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.
Paolo VitaleInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.
Guillermo GerardInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.
Leonardo Crespo-HerreraInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.ORCID 0000-0003-0506-4700
Susanne DreisigackerInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.ORCID 0000-0002-3546-5989
Carolina Saint PierreInternational Maize and Wheat Improvement Center (CIMMYT), Km 45, Carretera México-Veracruz, Texcoco 52640, EM, Mexico.ORCID 0000-0003-1291-7468
Luis G PosadasDepartment of Agronomy and Horticulture, University of Nebraska, 363 Keim Hall, Lincoln, NE 68583, USA.
Afolabi AgbonaInternational Institute of Tropical Agriculture (IITA), Ibadan 200001, Nigeria.
Raymundo Buenrostro-MariscalFacultad de Telemática, Universidad de Colima, Colima 28040, CL, Mexico.
Abelardo Montesinos-LópezCentro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, Guadalajara 44430, JA, Mexico.
Aakash ChawadeDepartment of Plant Breeding at SLU, Swedish University of Agricultural Sciences, P.O. Box 190 Alnarp, SE-23422 Lomma, Sweden.ORCID 0000-0002-6500-4139

Funding

SLU Sweedish Agricultural University Plain Breeding Department
6 · The paper itself

Abstract

Genomic selection (GS) accelerates plant breeding by predicting complex traits using genomic data. This study compares genomic best linear unbiased prediction (GBLUP), quantile mapping (QM)-an adjustment to GBLUP predictions-and four outlier detection methods. Using 14 real datasets, predictive accuracy was evaluated with Pearson's correlation (COR) and normalized root mean square error (NRMSE). GBLUP consistently outperformed all other methods, achieving an average COR of 0.65 and an NRMSE reduction of up to 10% compared to alternative approaches. The proportion of detected outliers was low (<7%), and their removal had minimal impact on GBLUP's predictive performance. QM provided slight improvements in datasets with skewed distributions but showed no significant advantage in well-distributed data. These findings confirm GBLUP's robustness and reliability, suggesting limited utility for QM when data deviations are minimal.

Indexed as

Chromosome MappingGenome, PlantGenomicsModels, GeneticPlant BreedingQuantitative Trait LociSelection, GeneticGBLUPgenomic predictionoutlier detection methodsplant breedingquantile mapping

Identifiers

PMID40332092
PMCPMC12026829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.