Evidence map›Paper›PMID 40332081›Full record

ArticleInternational journal of molecular sciences2025

Comparative Analysis of Localization and Composition of Adult Neurogenic Niches in the Chondrichthyans

Sara Bagnoli, Davide Lorenzo Drago, Emanuele Astoricchio, Elena Chiavacci, Baldassarre Fronte, Alessandro Cellerino, Eva Terzibasi Tozzini

Abstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara BagnoliBiology Laboratory (BIO@SNS), Scuola Normale Superiore, 56126 Pisa, Italy.ORCID 0000-0002-9491-5804
Davide Lorenzo DragoBiology Laboratory (BIO@SNS), Scuola Normale Superiore, 56126 Pisa, Italy.
Emanuele AstoricchioBiology and Evolution of Marine Organisms Department (BEOM), Stazione Zoologica Anton Dohrn, 80121 Napoli, Italy.ORCID 0000-0002-6394-9403
Elena ChiavacciBiology Laboratory (BIO@SNS), Scuola Normale Superiore, 56126 Pisa, Italy.ORCID 0000-0003-3924-3635
Baldassarre FronteDepartment of Veterinary Sciences, University of Pisa, 56124 Pisa, Italy.
Alessandro CellerinoBiology Laboratory (BIO@SNS), Scuola Normale Superiore, 56126 Pisa, Italy.
Eva Terzibasi TozziniBiology and Evolution of Marine Organisms Department (BEOM), Stazione Zoologica Anton Dohrn, 80121 Napoli, Italy.ORCID 0000-0003-3317-1538

Funding

Scuola Normale Superiore RICBASE_2024_CELLERINOStazione Zoologica Anton Dohrn SZNTerzibasi
6 · The paper itself

Abstract

Adult neurogenesis in cartilaginous fish remains a relatively unexplored area, particularly in terms of comparative analysis. This process, defined as the ability of specialized stem cells to generate new functional neurons, has gained prominence due to its relevance in neurodegenerative disease research and regenerative medicine. However, there is an ongoing discussion about when and where it first appeared. Evidence of adult neurogenesis in both teleosts and mammals highlights significant differences, such as the number of newly formed cells and the brain regions involved. Investigating additional cartilaginous fish species, which occupy a basal position in vertebrate phylogeny, could provide valuable insights into the ancient origins of this trait and potentially new general knowledge about the adult neurogenesis process. In this study, we combined immunohistochemistry and in situ hybridization to examine neurogenic activity in three brain regions-the telencephalon, mesencephalon, and cerebellum-of two batoid species:

Indexed as

NeurogenesisSkates, FishStem Cell NicheAnimalsBrainMesencephalonNeural Stem CellsNeuronsTelencephalonadult neurogenesisneurogenic nichesPCNARaja asteriasS100BTorpedo ocellata

Identifiers

PMID40332081
PMCPMC12027359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.