Evidence map›Paper›PMID 40332073›Full record

ArticleInternational journal of molecular sciences2025

Disruption of Man-6-P-Dependent Sorting to Lysosomes Confers IGF1R-Mediated Apoptosis Resistance.

Asena Aynaci, Maxence Toussaint, Florentine Gilis, Martine Albert, Jean-François Gaussin, Michel Jadot, Marielle Boonen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asena AynaciLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.ORCID 0009-0002-3669-8888
Maxence ToussaintLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.ORCID 0009-0003-2043-7373
Florentine GilisLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.
Martine AlbertLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.
Jean-François GaussinLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.
Michel JadotLaboratory of Physiological Chemistry, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.ORCID 0000-0002-7425-3006
Marielle BoonenLaboratory of Intracellular Trafficking Biology, URPhyM, NARILIS, UNamur, 61 rue de Bruxelles, 5000 Namur, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in

Indexed as

ApoptosisLysosomesMannosephosphatesReceptor, IGF Type 1Transferases (Other Substituted Phosphate Groups)ChloroquineHeLa CellsHumansProtein TransportChloroquineGNPTAB protein, humanIGF1R protein, humanmannose-6-phosphateMannosephosphatesReceptor, IGF Type 1Transferases (Other Substituted Phosphate Groups)apoptosisGNPTABIGF1Rlysosomesmannose-6-phosphate, M6PRmucolipidosis II

Identifiers

PMID40332073
PMCPMC12026698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.