ArticleInternational journal of molecular sciences2025
Valorization of Pomegranate Peel: Mechanisms and Clinical Applications in Irritable Bowel Syndrome Management.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Peel of Pomegranate Fruit (Current issues in molecular biology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Current disposal methods for pomegranate peel (PP) waste are inadequate, resulting in environmental pollution. Given PP's therapeutic potential in alleviating irritable bowel syndrome (IBS), elucidating its bioactive mechanisms is critical to guide its development into dietary supplements and promote sustainable recycling. In this study, bioinformatics and network analysis were employed to identify active compounds, key targets, and signaling pathways associated with PP's therapeutic effects. We identified 39 bioactive compounds (primarily polyphenols) and 106 key targets linked to IBS. Network analyses revealed that PP polyphenols mitigate oxidative stress and inflammation, modulate estrogen receptors to enhance gastrointestinal motility, and regulate ferroptosis. These findings underscore PP's potential as a therapeutic agent for IBS and provide a framework for repurposing food-processing byproducts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.