Evidence map›Paper›PMID 40331978›Full record

ArticleInternational journal of molecular sciences2025

A Multi-Level Study on the Anti-Lung Cancer Mechanism of Peiminine, a Key Component of

Ziwen Yang, Shah Syed Faizan Ali, Xinhui Huang, Lin Wei, Yinze Zhong, Xuepeng Shi, Xiaotian Wu, Chunli Gan, Zhibin Wang, Chunjuan Yang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Polyporusterone E, a Key Component ofInternational journal of molecular sciences · 2026
    Article
  2. Determination and Pharmacokinetic of Peiminine in Beagle Dogs by UPLC-MS/MS.International journal of analytical chemistry · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ziwen YangDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Shah Syed Faizan AliDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Xinhui HuangDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Lin WeiDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Yinze ZhongDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Xuepeng ShiDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Xiaotian WuDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.
Chunli GanDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.ORCID 0000-0003-2235-745X
Zhibin WangKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, Heilongjiang University of Chinese Medicine, Harbin 150000, China.
Chunjuan YangDepartment of Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150000, China.

Funding

Heilongjiang Provincial Key Plan GA22B012the Heilongjiang Touyan Innovation Team Program Document Heilongjiang Head Goose Action 587 Leading Group (2019) No.5the Scientific Research Project of Natural Science Foundation of China 81872979
6 · The paper itself

Abstract

Globally, lung cancer is the primary cause of deaths associated with cancer; however, current therapies are costly and toxic, highlighting the need for novel treatments. Peiminine (Verticinone), a key bioactive compound derived from

Indexed as

Antineoplastic Agents, PhytogenicCevanesFritillariaLung NeoplasmsApoptosisCell Line, TumorChromatography, High Pressure LiquidComputational BiologyGene Expression Regulation, NeoplasticHumansMolecular Docking SimulationNetwork PharmacologyProtein Interaction MapsSignal TransductionTandem Mass SpectrometryAntineoplastic Agents, PhytogenicCevanespeimininelung cancermolecular dockingnetwork pharmacologypeimininePI3K–Akt signaling pathway

Identifiers

PMID40331978
PMCPMC12027391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.