Carvacrol Protects IPEC-J2 Cells from Oxidative Stress by Suppressing Autophagy.

Ming-Chun Hsu, Han-Tsung Wang, Ching-Yi Chen

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Investigating alterations associated with heat stress and the recovery of the intestinal barrier using IPEC-J2 as an intestinal epithelial porcine cell model.Scientific reports · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ming-Chun HsuDepartment of Animal Science and Technology, National Taiwan University, Taipei 10672, Taiwan.

Han-Tsung WangDepartment of Animal Science and Technology, National Taiwan University, Taipei 10672, Taiwan.ORCID 0000-0002-5142-8619

Ching-Yi ChenDepartment of Animal Science and Technology, National Taiwan University, Taipei 10672, Taiwan.ORCID 0000-0002-5776-084X

Funding

Ministry of Education, Taiwan NTU-JP-113L7229Ministry of Education, Taiwan NTU-JP-114L7201Ministry of Science and Technology, Taiwan MOST 110-2320-B-002-039-MY3

6 · The paper itself

Abstract

Oxidative stress impairs intestinal function and causes poor growth performance in piglets. Carvacrol is a natural essential oil, and its anti-oxidative and anti-inflammatory activities in the intestines of piglets have been reported in many studies. However, the mechanisms underlying these protective effects against oxidative stress remain unclear. This study aimed to investigate the possible pathway of carvacrol in the porcine intestine under oxidative stress using an in vitro model. Porcine intestinal epithelial cells (IPEC-J2) were treated with carvacrol and hydrogen peroxide (H

Indexed as

AutophagyCymenesEpithelial CellsOxidative StressAnimalsAntioxidantsApoptosisCell LineCell SurvivalHydrogen PeroxideIntestinal MucosaMalondialdehydeMitochondriaReactive Oxygen SpeciesSwineAntioxidantscarvacrolCymenesHydrogen PeroxideMalondialdehydeReactive Oxygen Speciesautophagycarvacrolintestinal healthmitochondrial dysfunctionoxidative stressweaning piglet

Identifiers

PMID40331969

DOI10.3390/ijms26083495

PMCPMC12026536

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.