Evidence map›Paper›PMID 40331955›Full record

ArticleInternational journal of molecular sciences2025

lncRNAs GAS5 and MALAT1 Contained in Human Adipose Stem Cell (hASC)-Derived Exosomes Drive the Cell-Free Repair and Regeneration of Wounds In Vivo.

Meredith Krause-Hauch, Rekha S Patel, Bangmei Wang, Brenna Osborne, Brianna Jones, Paul Albear, Niketa A Patel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meredith Krause-HauchResearch Service, James A. Haley Veterans' Hospital, 13000 Bruce B Downs Blvd, Tampa, FL 33612, USA.
Rekha S PatelResearch Service, James A. Haley Veterans' Hospital, 13000 Bruce B Downs Blvd, Tampa, FL 33612, USA.
Bangmei WangResearch Service, James A. Haley Veterans' Hospital, 13000 Bruce B Downs Blvd, Tampa, FL 33612, USA.
Brenna OsborneDepartment of Molecular Medicine, University of South Florida, Tampa, FL 33612, USA.
Brianna JonesDepartment of Chemistry, University of South Florida, Tampa, FL 33612, USA.
Paul AlbearResearch Service, James A. Haley Veterans' Hospital, 13000 Bruce B Downs Blvd, Tampa, FL 33612, USA.
Niketa A PatelResearch Service, James A. Haley Veterans' Hospital, 13000 Bruce B Downs Blvd, Tampa, FL 33612, USA.ORCID 0000-0003-4811-8596

Funding

BLRD VA I01 BX005591BLRD VA IK6 BX005387United States Department of Veterans Affairs I0 BX005591United States Department of Veterans Affairs IK6BX005387
6 · The paper itself

Abstract

Wound healing progresses through four phases: hemostasis, inflammation, proliferation, and remodeling. Wounds may become chronic if this process is disrupted. The use of small extracellular vesicle (sEV; EVs < 200 nm) exosomes (exo; ~40-120 nm) derived from human adipose stem cells (hASCs) as a treatment for wounds is well studied. The cargo of these exosomes is of great interest as this accelerates wound healing. Our previous studies identified lncRNAs

Indexed as

ExosomesRegenerationRNA, Long NoncodingStem CellsWound HealingAdipose TissueAnimalsHumansMaleRatsRats, Sprague-DawleyGAS5 long non-coding RNA, humanMALAT1 long non-coding RNA, humanRNA, Long Noncodingadipose stem cellsexosomesGas5Malat1RNAseqsmall extracellular vesicleswound healing

Identifiers

PMID40331955
PMCPMC12027045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.