Evidence map›Paper›PMID 40331681›Full record

ArticleMolecular pain

Electroacupuncture intervention relieves pain by stimulating the STING/IFN-I pathway in rat models of cancer-induced bone pain.

Yi-Ming Gu, Xiang Meng, Jia-Yi Liang, Yong Xia, Jun-Wei Huang, Ke Wang, Zi-Yong Ju

Abstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi-Ming GuShanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0009-0007-1894-2724
Xiang MengShanghai University of Traditional Chinese Medicine, Shanghai, China.
Jia-Yi LiangShanghai University of Traditional Chinese Medicine, Shanghai, China.
Yong XiaShanghai University of Traditional Chinese Medicine, Shanghai, China.
Jun-Wei HuangShanghai University of Traditional Chinese Medicine, Shanghai, China.
Ke WangYueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0000-0002-5845-7228
Zi-Yong JuShanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0000-0001-5823-2232

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effects of electroacupuncture (EA) on cancer-induced bone pain (CIBP) and investigate its interaction with the STING/IFN-I pathway. A CIBP model was established in female rats. EA was administered for six consecutive days at bilateral L3-L5 Jia Ji points (EX-B2). EA-induced antinociception was evaluated through mechanical, thermal, and cold sensitivity assessments. EA significantly increased the paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) in rats with CIBP (

Indexed as

Bone NeoplasmsCancer PainElectroacupunctureMembrane ProteinsSignal TransductionAnimalsDisease Models, AnimalFemaleRatsRats, Sprague-DawleyMembrane Proteinsanalgesic effectscancer-induced bone painelectroacupunctureIFN-ISTING

Identifiers

PMID40331681
PMCPMC12144371

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.