Evidence map›Paper›PMID 40331480›Full record

ArticleDevelopmental science2025

Prenatal Household Income Instability and Infant Subcortical Brain Volumes.

Genevieve Patterson, Alexander J Dufford, Taryn W Morrissey, Martin Styner, Sun Hyung Kim, Pilyoung Kim

Abstract read
In one paragraph

Article in Developmental science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Perinatal hardship and infant neurodevelopment: insights from a global pandemic.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Genevieve PattersonDepartment of Psychology, University of Denver, Denver, Colorado, USA.ORCID https://orcid.org/0000-0001-7983-2616
Alexander J DuffordCenter for Mental Health Innovation, Oregon Health & Science University, Portland, Oregon, USA.
Taryn W MorrisseySchool of Public Affairs, American University, Washington, District of Columbia, USA.
Martin StynerDepartment of Psychiatry, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA.
Sun Hyung KimDepartment of Psychiatry, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA.
Pilyoung KimDepartment of Psychology, University of Denver, Denver, Colorado, USA.

Funding

Prenatal Pathways for Poverty’s Influence on the Brains of Two GenerationsR01HD090068 · NICHD · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KIM, PILYOUNG · 2017 to 2022
$2.8M
Cannabis Use during Pregnancy, Maternal Brain, and Mother-Infant RelationshipsR21DA046556 · NIDA · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KIM, PILYOUNG · 2018 to 2019
$422k
NICHD NIH HHS R01 HD090068NIDA NIH HHS R21 DA046556
6 · The paper itself

Abstract

Prenatal stress exposure may negatively influence the development of the amygdala and hippocampus. Although there is significant income instability during pregnancy, and it can increase stress among pregnant parents, the impact of income instability on brain development is not well understood. The present study examined the association between household income losses during pregnancy and hippocampus and amygdala volumes in early infancy. A total of 63 infants from a prospective longitudinal study of pregnant individuals and their infants completed an MRI during natural sleep. The total number of negative month-to-month earnings shocks (defined as an arc percent change [APC] of -25 or greater) was significantly associated with smaller right hippocampal and right amygdala volumes. This suggests that household income losses during the perinatal period are associated with infant brain structure after birth. These findings provide support for the development of public programs that prioritize financial consistency, especially during sensitive periods like pregnancy.

Indexed as

AmygdalaHippocampusIncomePrenatal Exposure Delayed EffectsStress, PsychologicalAdultEconomic StabilityFemaleFetal DevelopmentHumansInfantLongitudinal StudiesMagnetic Resonance ImagingMalePregnancyYoung Adultamygdalahippocampusincome instabilityinfant brain

Identifiers

PMID40331480
PMCPMC12056889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.