Evidence map›Paper›PMID 40331429›Full record

ArticleNucleic acids research2025

Web-based GTalign: bridging speed and accuracy in protein structure analysis.

Justas Dapkūnas, Mindaugas Margelevičius

Abstract read
In one paragraph

Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Justas DapkūnasInstitute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio av. 7, 10257 Vilnius, Lithuania.ORCID 0000-0002-0496-6107
Mindaugas MargelevičiusInstitute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekio av. 7, 10257 Vilnius, Lithuania.ORCID 0000-0003-4981-6708

Funding

Lithuanian Research Library Consortium (LMBA)NVIDIAResearch Council of Lithuania S-MIP-23-104Research Council of Lithuania S-MIP-23-44
6 · The paper itself

Abstract

Accurate protein structure alignment is essential for understanding structural and functional relationships. Here, we introduce GTalign-web, a web-based implementation of GTalign, a spatial index-driven protein structure alignment tool, designed for accessibility and high-performance structural searches. Benchmarked against the DALI and Foldseek servers, GTalign-web demonstrates superior accuracy while maintaining rapid search times. Its utility is further highlighted in annotating uncharacterized proteins through searches against UniRef30. GTalign-web provides a useful resource for protein structure analysis and functional annotation and is available at https://bioinformatics.lt/comer/gtalign. This website is free and open to all users, and there is no login requirement.

Indexed as

ProteinsSoftwareDatabases, ProteinInternetProtein ConformationSequence AlignmentProteins

Identifiers

PMID40331429
PMCPMC12230656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.