ArticleThe journal of adhesive dentistry2025
The Incorporation of Copper-Doped Bioactive Glass Nanoparticles into Resin Composites Improves Their Biological, Mechanical and Adhesive Properties.
Article in The journal of adhesive dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to develop and characterize copper-doped bioactive glass nanoparticles (BG/CuNp), and to evaluate the effects of their addition into a resin composite on antimicrobial activity (AMA), cytotoxicity (CTX), ultimate tensile strength (UTS), Knoop microhardness (KHN), as well as immediate resin-dentin microtensile bond strength (μTBS), nanoleakage (NL) and in-situ degree of conversion (DC). MATERIALS AND
methodsBG/CuNp were added to a resin composite at different concentrations (0% [control]; 5, 10 and 20 wt%). The AMA was evaluated against Streptococcus mutans. For CTX, the Gingival mesenchymal stem cells (GMSC) cell line was used. For UTS and KHN, specimens were tested after 24 h and 28 days. For bonding evaluation, a universal adhesive was applied on flat dentin surfaces, experimental resin composite build-ups were prepared, and specimens were sectioned to obtain resin-dentin sticks. These were evaluated for μTBS, NL and DC after water storage. Data were submitted to statistical analyses (α = 0.05).
resultsThe addition of 5% and 10% of BG/CuNp increases AMA (P 0.05), while the CTX remained unchanged with resin-containing BG/CuNp (P > 0.05). UTS and KHN remained stable with the addition of 5% and 10% of BG/CuNp at 24 h, but showed significantly higher values compared to the control after 28 d (P 0.05). μTBS and in-situ DC remained unchanged with BG/CuNp addition, regardless of the concentration added. However, significantly lower NL was observed for BG/CuNp groups (P 0.05).
conclusionThe addition of BG/CuNp in the tested concentrations into a resin composite may be an alternative to provide antimicrobial activity and improve the integrity of the hybrid layer, without compromising biological, adhesives and mechanical properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.