Evidence map›Paper›PMID 40331257›Full record

ArticleThe Canadian journal of urology2025

The cost and guideline adherence of direct-to-consumer telemedicine companies offering gender-affirming hormone therapy.

Nicholas Sellke, Erin Jesse, Justin M Dubin, Tomislav D Medved, Neha S Basti, Janvi Ramchandra, Robert E Brannigan, Joshua A Halpern, Nannan Thirumavalavan

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Article in The Canadian journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nicholas SellkeUrology Institute, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Erin JesseUrology Institute, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Justin M DubinDepartment of Urology, Memorial Healthcare System, Hollywood, FL 33021, USA.
Tomislav D MedvedUrology Institute, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Neha S BastiDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Janvi RamchandraCase Western Reserve University, Cleveland, OH 44106, USA.
Robert E BranniganDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Joshua A HalpernDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Nannan ThirumavalavanUrology Institute, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDirect-to-consumer (DTC) telemedicine has emerged as an option for transgender patients seeking gender affirming hormone therapy (GAHT). We aimed to characterize the healthcare services provided by DTC telemedicine companies offering GAHT and to compare their costs to a tertiary care center.

methodsWe identified DTC telemedicine platforms offering GAHT via internet searches and extracted information from their websites related to evaluation, treatment, monitoring, and cost. Cost of the DTC GAHT was compared to cost for comparable services at a tertiary care center.

resultsSix DTC companies were identified. All platforms utilized an informed consent model without prerequisite mental health evaluation for GAHT. Platforms did not provide comprehensive mental health services. All platforms endorsed the use of regular follow up visits throughout the treatment period although interval of laboratory assessment varied. Cost estimates were comparable for uninsured patients and higher compared to those for insured patients. Cost estimates were lowest with private and public insurance at the tertiary center.

conclusionsDTC telemedicine platforms offering GAHT appear to be in line with the recently released World Professional Association for Transgender Health standards of care regarding the laboratory evaluation and monitoring, but it is unclear whether they are compliant with other recommendations. These platforms offer competitive costs for TGD patients without insurance.

Indexed as

Gender-Affirming ProceduresGuideline AdherenceTelemedicineFemaleHumansMaleTransgender Personsdirect-to-consumerestradiolhealth care costshealth services for transgender personstelemedicinetestosterone

Identifiers

PMID40331257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.