Evidence map›Paper›PMID 40331211›Full record

ArticleJournal of biomolecular techniques : JBT2024

Quality Control in the Mass Spectrometry Proteomics Core: A Practical Primer.

Benjamin A Neely, Yasset Perez-Riverol, Magnus Palmblad

Abstract read
In one paragraph

Article in Journal of biomolecular techniques : JBT, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamin A NeelyNational Institute of Standards and Technology CharlestonSC USA.ORCID 0000-0001-6120-7695
Yasset Perez-RiverolEuropean Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Wellcome Trust Genome Campus HinxtonCambridge United Kingdom.ORCID 0000-0001-6579-6941
Magnus PalmbladCenter for Proteomics and Metabolomics Leiden University Medical Center Leiden The Netherlands.ORCID 0000-0002-5865-8994

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past decade has seen widespread advances in quality control (QC) materials and software tools focused specifically on mass spectrometry-based proteomics, yet the rate of adoption is inconsistent. Despite the fundamental importance of QC, it typically falls behind learning new techniques, instruments, or software. Considering how important QC is in a core setting where data is generated for non-mass spectrometry experts and confidence in delivered results is paramount, we have created this quick-start guide focusing on off-the-shelf QC materials and relatively easy-to-use QC software. We hope that by providing a background on the different levels of QC, different materials and their uses, describing QC design options, and highlighting some current QC software, implementing QC in a core setting will be easier than ever. There continues to be development in each of these areas (such as new materials and software), and the current generation of QC for mass spectrometry-based proteomics is more than capable of conveying confidence in results as well as minimizing laboratory downtime by guiding experimental, technical, and analytical troubleshooting from sample to results.

Indexed as

Mass SpectrometryProteomicsQuality ControlHumansSoftwarebest practicesmaterialsproteomicsquality controlsoftwarestandards

Identifiers

PMID40331211
PMCPMC12051443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.