Evidence map›Paper›PMID 40331150›Full record

ReviewMaterials today. Bio2025

Recent advances in fluorescent nanomaterials designed for biomarker detection and imaging.

Xuming Sun, Tong Xiang, Linyan Xie, Qiongqiong Ren, Jinlong Chang, Wenshuai Jiang, Zhen Jin, Xiuli Yang, Wu Ren, Yi Yu

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  10. Advances in Immunological Methods for the Detection ofSensors (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xuming SunSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Tong XiangSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Linyan XieSchool of Mathematical Medicine, Xinxiang Medical University, Xinxiang, 453003, PR China.
Qiongqiong RenSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Jinlong ChangSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Wenshuai JiangSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Zhen JinSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Xiuli YangDepartment of Cardiology, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453003, PR China.
Wu RenSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.
Yi YuSchool of Medical Engineering, Xinxiang Medical University, Xinxiang, 453003, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The highly sensitive detection and imaging of biomarkers are critical for early diagnosis, treatment, and prognosis monitoring. The unique size and structure of fluorescent nanomaterials provide key benefits such as excellent photostability, high fluorescence quantum yield, and tunable excitation and emission wavelengths. These properties have led to the widespread application of nanomaterials in fluorescent biomarkers detection and imaging. In this review, we began by introducing the composition of fluorescent probes and discussing the underlying sensing mechanisms. We then summarized recent advances in the use of fluorescent nanomaterials such as quantum dots (QDs), metal nanoclusters (MNCs), carbon dots (CDs), and metal-organic frameworks (MOFs) for biomarker detection and imaging. Additionally, we highlighted the applications of fluorescent nanomaterials in the detection and imaging of small molecules, biomacromolecules, and various biomarkers, including metal ions, bacteria, and circulating tumor cells (CTCs). The challenges and future prospects of fluorescent nanomaterials in biomarker detection and imaging were also discussed. We anticipate that fluorescent nanomaterials will have profound implications for clinical biomarker detection and imaging, with considerable application in both academic research and industrial applications.

Indexed as

BiomarkerFluorescenceImagingNanomaterials

Identifiers

PMID40331150
PMCPMC12053759

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.