Evidence map›Paper›PMID 40330957›Full record

ArticleRomanian journal of ophthalmology

Hidden peril: Large ciliary body melanoma imitating cataract in a cardiac patient.

Sonali Vinay Kumar, Manoj Gopal Madakshira, Vinay Kumar, Natasha Vinay Kumar, Sourabh Kumar

Abstract readCase Reports
In one paragraph

Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonali Vinay Kumar(Ophthalmology), Command Hospital Eastern Command, Kolkata, West Bengal, India.
Manoj Gopal Madakshira(Pathology), Command Hospital Eastern Command, Kolkata, West Bengal, India.
Vinay Kumar(Anatomy), JIS School of Medical Science and Research, Howrah, West Bengal, India.
Natasha Vinay KumarDepartment of Medicine, Sri Devaraj Urs Medical College, Kolar, Karnataka, India.
Sourabh Kumar(Ophthalmology), Command Hospital Eastern Command, Kolkata, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ciliary body melanoma is a rare and aggressive ocular tumor that often presents with nonspecific symptoms, leading to delayed diagnosis. This report presents the case of a 43-year-old male with a history of ischemic heart disease who presented with diminished vision in the left eye, initially attributed to a cataract. Despite prior evaluation, no sign of malignancy was detected, and the patient was advised to proceed with cataract surgery. The patient visited our center for a second opinion, where a comprehensive evaluation identified a large ciliary body melanoma extending into the anterior chamber. Management was challenging due to the patient's cardiac condition, as anticoagulant therapy could not be discontinued. Enucleation was performed to mitigate the high risk of hematogenous metastasis associated with the tumor's rich vasculature, ciliary body contraction, and potential extension through emissary canals. Histopathology confirmed the diagnosis of spindle cell melanoma. This case highlights the diagnostic complexities of ciliary body melanoma, which can masquerade as a common condition like cataract, emphasizing the need for vigilance in atypical presentations and the importance of thorough evaluation to avoid misdiagnosis. It also underscores the challenges in managing such tumors in patients with significant systemic comorbidities, requiring a multidisciplinary approach for optimal outcomes.

Indexed as

CataractCiliary BodyMelanomaUveal NeoplasmsAdultDiagnosis, DifferentialEye EnucleationHumansMaleUveal Melanomacataractciliary body melanomadelayed diagnosisenucleationHPE = histopathological examinationIOL = Intraocular lenslargemetastasisMRI = magnetic resonance imagingPET = positron emission tomographyUBM = ultrasound biomicroscopy

Identifiers

PMID40330957
PMCPMC12049655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.