Evidence map›Paper›PMID 40330868›Full record

ArticleJournal of oral microbiology2025

DNA virus tropism in healthy dental pulp: an in-situ reservoir site for torque teno virus and parvovirus B19.

O I Mielonen, S Hänninen, J Willberg, T Salo, M Mauramo

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

O I MielonenDepartment of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-6878-5770
S HänninenDepartment of Pathology, Research Program in Systems Oncology, Research Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
J WillbergDepartment of Oral Pathology and Oral Radiology, University of Turku, Turku, Finland.
T SaloDepartment of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-6039-0088
M MauramoDepartment of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.ORCID https://orcid.org/0000-0002-0107-4939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The presence of viruses in healthy teeth has not been extensively studied, although some viral traces have been detected in both healthy and diseased dental pulps in previous studies focusing primarily on a single species. The aim of this study is to clarify the persistence of DNA viruses in dental tissues and their impact on tissue composition. Materials and Methods: Here, the prevalence of persistent DNA viruses in intact third molars ( Results: Viral DNA of five different viruses was detected in 5 of the 17 samples (29.4%) including B19V ( Conclusions: These findings emphasized that even in the absence of a disease evaluated by histology, dental pulp can harbor DNA viruses and be an anatomical site of virus tropism, suggesting viral persistence rather than direct pathogenic activity.

Indexed as

DNA viruseshuman hard tissueodontologyqPCRRNAscope in-situ hybridizationTechnovit® 9100Virology

Identifiers

PMID40330868
PMCPMC12051552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.