Evidence map›Paper›PMID 40330865›Full record

ArticleDEN open2026

Prognostic factors and long-term outcomes with endoscopic submucosal dissection for colorectal tumors in patients aged 75 years or older.

Takaya Miura, Satohiro Matsumoto, Azumi Sato, Shu Kojima, Goya Sasaki, Mina Morino, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takehiro Ishii and 7 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Outcome and Prognostic Factors of Colorectal Endoscopic Submucosal Dissection in Patients Aged Over 75 Years.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Takaya MiuraDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.ORCID https://orcid.org/0009-0006-3477-9747
Satohiro MatsumotoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Azumi SatoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Shu KojimaDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Goya SasakiDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Mina MorinoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Keita MatsumotoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Hitomi KashimaDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Yudai KoitoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Takehiro IshiiDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Shuhei YoshikawaDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Haruka OtakeDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Takeshi UeharaDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Masanari SekineDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.ORCID https://orcid.org/0000-0002-8417-8804
Takeharu AsanoDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.
Hiroyuki MiyataniDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.ORCID https://orcid.org/0000-0003-3285-824X
Hirosato MashimaDepartment of Gastroenterology Jichi Medical University Saitama Medical Center Saitama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Studies regarding the long-term outcomes of endoscopic submucosal dissection (ESD) performed in older patients with colorectal tumors are limited. Therefore, in this study, we aimed to analyze the long-term outcomes of older patients with colorectal tumors who underwent ESD and identify prognostic factors. Methods: The data of patients aged ≥ 75 years who underwent ESD for colorectal tumors (adenoma and Tis/T1 colorectal cancer) at a single center were retrospectively analyzed. Prognostic factors for overall survival were analyzed using the Kaplan-Meier method and the Cox proportional hazard model. Results: Of the 156 patients included, 51 patients died during the follow-up period, among whom two deaths were due to colorectal cancer. The univariate analysis revealed that an age ≥83 years, Charlson Comorbidity Index ≥2, prognostic nutritional index <46, and neutrophil-to-lymphocyte ratio (NLR) ≥3 were associated with poor overall survival. The multivariate analysis identified Charlson Comorbidity Index ≥2 (hazard ratio: 2.26; 95% confidence interval (CI): 1.24-4.13; Conclusions: CCI and NLR may be useful parameters for decision-making in older patients undergoing colorectal ESD.

Indexed as

colorectal tumorsendoscopic submucosal dissectionlong‐term outcomesolder patientsprognostic factors

Identifiers

PMID40330865
PMCPMC12054497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.