Evidence map›Paper›PMID 40330727›Full record

ArticleFrontiers in microbiology2025

Urinary and oral microbiota in Polish women: a pilot case-control study of breast cancer.

Anna Marciniak, Marzena Skrzypczak-Zielińska, Oliwia Zakerska-Banaszak, Elżbieta Nowakowska, Anna Kozaczka, Brunon Zemła, Andrzej Szpak, Dariusz Godlewski, Jadwiga Charzewska, Dorothy R Pathak

Abstract read
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Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna MarciniakCenter of Cancer Prevention and Epidemiology OPEN, Poznan, Poland.
Marzena Skrzypczak-ZielińskaInstitute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Oliwia Zakerska-BanaszakInstitute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
Elżbieta NowakowskaAffidea International Cancer Center Poznań, Poznan, Poland.
Anna KozaczkaDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland.
Brunon ZemłaDepartment of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie Memorial Cancer Centre and Institute of Oncology, Gliwice, Poland.
Andrzej SzpakWitold Chodźko Institute of Rural Medicine, Lublin, Poland.
Dariusz GodlewskiCenter of Cancer Prevention and Epidemiology OPEN, Poznan, Poland.
Jadwiga CharzewskaDepartment of Nutrition and Nutritional Value of Food, National Institute of Public Health NIH-National Research Institute, Warsaw, Poland.
Dorothy R PathakDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The human microbiota can be a critical component in the development and progression of various diseases, including cancer. This study aims to investigate the composition of the urinary and oral microbiota in Polish breast cancer (BC) patients relative to healthy controls (HCs) and to predict relevant metabolic pathways of microbiota in studied groups. Methods: Urine and oral samples from 48 participants, 24 BC cases and 24 HCs, randomly selected from 417 BC cases and 514 HCs, were analyzed using next-generation sequencing of bacterial 16S rRNA gene (V1-V9) and fungal ITS regions, along with bioinformatics tools to identify and compare microbial communities and predict relevant pathways of microbiota in the studied groups. Results: BC case urine microbiota contained an increased abundance of Discussion: The study underscores the potential significance of the microbiota in BC pathogenesis. Further research is needed to elucidate the mechanisms underlying microbiota-tumor interactions and to explore the clinical applications.

Indexed as

breast cancerfunctional analysisnext-generation sequencingoral microbiotaurinary microbiota

Identifiers

PMID40330727
PMCPMC12054997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.