ArticleEuropean heart journal. Case reports2025
Missed transthoracic echocardiography diagnosis of unruptured sinus of Valsalva aneurysm with thrombus: a case report.
Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Unruptured sinus of Valsalva aneurysm (SVA) is a rare congenital or acquired cardiac lesion. It may remain asymptomatic or present with various clinical manifestations due to its 'mass effect' on the coronary arteries, valves, atria, and other adjacent structures. Unruptured SVA also carries the risk of secondary complications such as infection, thrombosis, and rupture, posing a serious threat to patient health. Case summary: A 55-year-old male from the central region of China, who presented with chest tightness following COVID-19 infection, underwent transthoracic echocardiography (TTE) one year before, which revealed an unruptured non-coronary SVA. Recent follow-up TTE showed findings consistent with the previous examination. Coronary computed tomography angiography (CCTA) subsequently demonstrated a non-coronary SVA complicated by a large thrombus and atherosclerotic changes in the aortic sinus wall. Due to the significant risk of thrombus dislodgement and subsequent systemic embolism, the patient underwent surgical thrombectomy and plasty of the non-coronary SVA. Intraoperative transoesophageal echocardiography (TEE) and surgical exploration confirmed the presence of a mural thrombus; while the potential association between COVID-19 infection and aneurysm formation remains to be fully elucidated. At the 6-month postoperative follow-up, the patient demonstrated favourable physical recovery, with no reported thrombo-embolic events (e.g. stroke or systemic embolism), recurrent symptoms, or other adverse clinical outcomes. A repeat TTE during follow-up revealed a well-preserved aortic root morphology, with normal dimensions and no signs of residual aneurysm or valvular dysfunction. Discussion: We report a unique instance of a massive thrombosed non-coronary SVA. Considering the limitations of TTE and its low sensitivity to SVA secondary lesions, it is recommended to further perform TEE or CCTA to comprehensively evaluate the morphology and structure of SVA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.