Evidence map›Paper›PMID 40330407›Full record

ArticleCureus2025

A Unique Case of Biventricular Arrhythmogenic Cardiomyopathy.

Aakash Rana, Jack Xu, Jin Zhao

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aakash RanaMedicine, Central Arkansas Veterans Healthcare System, Little Rock, USA.
Jack XuCardiology, Novant Health, Winston-Salem, USA.
Jin ZhaoCardiology, Novant Health, Winston-Salem, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arrhythmogenic cardiomyopathy is a type of heart disease that is a well-recognized cause of sudden cardiac death among the young population. It can affect the right ventricle, left ventricle, or both ventricles of the heart. This condition involves the replacement of heart muscle with fatty tissue, which can disrupt the heart's normal electrical and mechanical function, leading to arrhythmias, heart failure, and increased risk of sudden cardiac death. We report the case of a 62-year-old man who came to the emergency room with nausea, vomiting, and palpitations. After further evaluation, he was diagnosed with heart failure secondary to biventricular arrhythmogenic cardiomyopathy. The patient was found to have a genetic mutation in the RYR2 gene, which usually causes dilation of the right ventricle. However, in this case, both the right and left ventricles were dilated, which is unusual since RYR2 mutations are typically linked to right ventricle dilation only. This may represent a potentially novel phenotypic manifestation of the disease associated with this mutation, as no other cases have been reported in the literature.

Indexed as

arrhythmogenic cardiomyopathyarrhythmogenic disordersarrhythmogenic right ventricular cardiomyopathyepsilon wavessudden cardiac death

Identifiers

PMID40330407
PMCPMC12053726

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.