Evidence map›Paper›PMID 40330400›Full record

ReviewCureus2025

Assessing the Adverse Effects and Safety Concerns Related to Cosmetic and Skincare Products: A Systematic Review.

Rimaz Sami Alyahya, Maha A AlHasson, Mnahal A Ali Alhsaon

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rimaz Sami AlyahyaDermatology, Qassim University, Riyadh, SAU.
Maha A AlHassonGynecologist, King Fahad Specialist Hospital, Qassim, SAU.
Mnahal A Ali AlhsaonFamily Medicine, Department of Public Health, Qassim Health Cluster, Qassim, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cosmetics and personal care products are essential for personal hygiene and appearance; however, their safety remains a key concern due to associated adverse effects. This systematic review aims to evaluate the adverse effects and safety concerns related to skincare products and to analyze product characteristics and usage patterns for improved consumer safety. The study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and adopted diverse database searches across PubMed, Medline, Google Scholar, and Scopus from 2014-2024. Only peer-reviewed and cross-sectional studies were included along with a data extraction sheet, and the Critical Appraisal Skills Programme (CASP) tool was utilized for quality assessment. Data synthesis involved descriptive and qualitative analysis to identify common themes and implications. Nine studies were included in the review, comprising 4,569 participants across geographically diverse regions. The common adverse effects reported included acne (36%), redness (27%), itching (19%), and skin irritation (18%). Ingredient analysis identified that fragrances, preservatives, and colorants are commonly related to adverse effects. Usage patterns like frequency and duration of usage were correlated with the likelihood of adverse effects. The review focused on significant adverse effects linked with cosmetic and personal care products, highlighting the necessity for better awareness, clear labels, and strict regulations. Enhanced customer education and following safety protocols are crucial to minimize risks and ensure product safety.

Indexed as

adverse effectscosmetic safetypersonal care productsskincare productssystematic review

Identifiers

PMID40330400
PMCPMC12051748

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.