Evidence map›Paper›PMID 40330355›Full record

ReviewCureus2025

Systematic Review of Cryptococcus neoformans Seroprevalence, Antifungal Susceptibility, and Pathogenesis in Patients With HIV/AIDS on Combination Antiretroviral Therapy in Abuja, Nigeria.

Gloria C Ifiora, Ijeje Sule, Edediong Ekarika, Chigozie D Opara, Henry Adebayo

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gloria C IfioraPharmaceutical Microbiology, Nnamdi Azikiwe University, Awka, NGA.
Ijeje SuleCardiology, Red Deer Regional Hospital Centre, Red Deer, CAN.
Edediong EkarikaPublic Health, Emory Rollins School of Public Health, Atlanta, USA.
Chigozie D OparaMedicine and Surgery, Imo State University, Owerri, NGA.
Henry AdebayoOrthodontics, University of Benin, Benin City, NGA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For individuals living with HIV/AIDS in low-resource settings such as Sub-Saharan African countries, including Nigeria, cryptococcal meningitis (CM) is a significant contributor to both mortality and morbidity. Despite advancements in antiretroviral therapy (ART), which have markedly transformed the treatment and management of HIV, CM remains a considerable challenge. It primarily arises from delays in diagnosis, limited access to antifungal treatments, and a lack of healthcare resources and infrastructure. With the historical correlation between the rising prevalence of HIV/AIDS and the increased incidence of

Indexed as

antiretroviral therapycombination antiretroviral therapy (cart)cryptococcosiscryptococcus neoformans (c. neoformans)people living with hiv/aids

Identifiers

PMID40330355
PMCPMC12050352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.