Evidence map›Paper›PMID 40330210›Full record

ReviewFood science & nutrition2025

Effects of Spirulina Supplementation on C-Reactive Protein (CRP): A Systematic Review and Dose-Response Meta-Analysis.

Mostafa Shahraki Jazinaki, Mohammad Rashidmayvan, Pegah Rahbarinejad, Mohammad Reza Shadmand Foumani Moghadam, Naseh Pahlavani

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecules (Basel, Switzerland) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mostafa Shahraki JazinakiDepartment of Nutrition, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0009-0006-6526-8712
Mohammad RashidmayvanDepartment of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center Gonabad University of Medical Sciences Gonabad Iran.
Pegah RahbarinejadDepartment of Nutrition, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.
Mohammad Reza Shadmand Foumani MoghadamService of Clinical Nutrition and Dietitian, Emam Reza Hospital Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-7431-7869
Naseh PahlavaniHealth Sciences Research Center Torbat Heydariyeh University of Medical Sciences Torbat Heydariyeh Iran.ORCID https://orcid.org/0000-0002-2592-5646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The preceding research has produced varied results concerning the impact of Spirulina supplementation on C-reactive protein (CRP) levels, considered one of the primary risk factors associated with inflammation in chronic conditions. We aimed to understand the potential relationship between Spirulina supplementation and human CRP modulation by performing a meta-analysis. A comprehensive search was conducted up to February 2024 on prominent medical bibliographic databases, including Web of Science, Scopus, and PubMed, to identify relevant studies. The overall effect size was calculated using a random-effects model that was proposed by DerSimonian and Laird. The pooled effect size was expressed as weighted mean differences (WMD) with 95% confidence intervals (CI). Furthermore, the heterogeneity between the included studies was evaluated using Cochran's

Indexed as

cardiovascular diseasesC‐reactive proteininflammationspirulina

Identifiers

PMID40330210
PMCPMC12052714

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.