ArticlePlastic and reconstructive surgery. Global open2025
A Prospective Study to Evaluate the SPY-QP Software for Intraoperative Perfusion Assessment in Breast Reconstruction.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Intraoperative Umbilical Perfusion Assessment Following Deep Inferior Epigastric Perforator Breast Reconstruction Using Indocyanine Green.Plastic and reconstructive surgery. Global open · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Laser-assisted indocyanine green angiography image quantification programs have been developed to guide the resection of ischemic tissue, but prior iterations have proved difficult to interpret. This study assesses outcomes using SPY-QP, a novel quantification algorithm of the SPY Portable Handheld Imaging system (Stryker Corporation). Methods: A prospective study was designed to enroll patients who underwent breast reconstruction with implant-based or autologous techniques. A prospective database of patient demographics, operative details, and outcomes at 2-week, 1-month, and 3-month follow-ups were maintained. Postoperative skin necrosis, fat necrosis, and infection, among other metrics, were correlated with indocyanine green angiography relative values (%). Logistic regressions were conducted using R-Studio. Results: Overall, 39 patients and 59 breasts were included in this study. Forty-nine (83.5%) breasts underwent implant-based reconstruction, whereas 10 (17.0%) were reconstructed with autologous tissue. Five (12.8%) patients had evidence of skin necrosis, 6 (15.4%) of fat necrosis, and 9 (23.1%) of postoperative infection. Of the patients with skin necrosis, 2 (40%) patients underwent local wound care, 2 (40%) patients required bedside debridement, and 1 (20%) patient required an operative debridement. Mean relative values were significantly lower in patients with skin necrosis in comparison to patients without skin necrosis (14.6%±12.4% versus 24.4%±13.4%, Conclusions: The SPY-QP technology is highly specific at low values and can effectively guide surgeons in the resection of ischemic tissue. Conversely, it remains challenging to predict necrosis in gray zones.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.