Evidence map›Paper›PMID 40330106›Full record

ArticleJournal of Alzheimer's disease reports

Association between visual hallucinations and cognitive performance in Lewy body dementia and Alzheimer's disease: A cross-sectional study.

Yaqi Yang, Fan Yang, Jinghuan Gan, Shuai Liu, Chen Wen, Lixin Liu, Tianjiao Ren, Jiarui Wang, Yong Ji

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yaqi YangDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0008-4982-4592
Fan YangDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0002-6497-2362
Jinghuan GanDepartment of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-8840-2834
Shuai LiuDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0001-3483-3049
Chen WenDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China.ORCID https://orcid.org/0009-0003-7994-3692
Lixin LiuDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0007-7412-5884
Tianjiao RenDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0007-8518-2622
Jiarui WangDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0009-0001-6234-5237
Yong JiDepartment of Neurology, Tianjin Huanhu Hospital, Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0000-0002-2191-6996

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Visual hallucinations (VH) are an important neuropsychiatric feature of dementia. The association between VH and cognition remains controversial. Objective: To investigate the differences in clinical correlates of VH and explore the associations between VH and cognitive functional decline in individuals with dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Methods: Outpatient medical records of 154 patients with DLB and 297 patients with AD between January 2017 and December 2023 were reviewed. We collected demographic characteristics and used neuropsychological assessments and semi-structured detailed interviews to evaluate cognition and VH. Multiple linear regression and mediation analyses were employed to analyze the data, adjusting for confounding variables. Results: DLB patients had a higher prevalence of VH than AD patients (p < 0.01). The presence of VH predicted lower Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scores in both DLB and AD patients (p < 0.01). In DLB patients, VH were associated with lower attention function scores after adjustment (p = 0.027). In AD patients, VH were related to worsened orientation ability after adjustment (p = 0.033). Attention function partially mediated the association between VH and cognition in DLB patients (p < 0.01), whereas orientation function partially mediated this association in AD patients (p < 0.01). Conclusions: VH may independently correlate with deterioration in global cognitive performance. In DLB patients with VH, attentional function appears to be more impaired, whereas in AD patients, orientation function is the most affected. Different cognitive domains may help distinguish between DLB and AD patients with VH.

Indexed as

Alzheimer's diseasecognitive impairmentdementiaLewy bodiesvisual hallucinations

Identifiers

PMID40330106
PMCPMC12053050

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.