Evidence map›Paper›PMID 40329982›Full record

ReviewJournal of biomolecular techniques : JBT2025

Light Microscopy as a Tool to Detect Apoptosis and Other Cellular Changes and Damage.

Richard W Cole, Danielle Hunt

Abstract readReview
In one paragraph

Review in Journal of biomolecular techniques : JBT, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Richard W ColeNew York State Department of Health Wadsworth Center.
Danielle HuntNew York State Department of Health Wadsworth Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light microscopy is a powerful tool that can detect and measure cellular and subcellular structural changes over time. This can be done quickly with transmitted light microscopy without perturbing the cells with stains or probes. For instance, cells undergoing apoptosis often shrink in size and have characteristic blebs in the plasma membrane. Many fluorescent probes/reporters are also used for different phases of apoptosis, such as tagged caspase 3. This paper will showcase the practical applications of several imaging modalities (transmitted light and fluorescence) for detecting apoptosis in endpoint and time-lapse images/sequences.

Indexed as

ApoptosisMicroscopyAnimalsCaspase 3Cell MembraneFluorescent DyesHumansMicroscopy, FluorescenceTime-Lapse ImagingCaspase 3Fluorescent Dyes

Identifiers

PMID40329982
PMCPMC12051451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.