Evidence map›Paper›PMID 40329693›Full record

ReviewJournal of separation science2025

Recent Developments in Deep Eutectic Solvents Applications in Liquid Chromatography: 2019-2025.

Derya Demir, Joanna Antos, František Švec, Hana Sklenářová

Abstract readReview
In one paragraph

Review in Journal of separation science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Derya DemirDepartment of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Joanna AntosDepartment of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
František ŠvecDepartment of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.
Hana SklenářováDepartment of Analytical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.

Funding

Charles University SVV 260782European Union under the ATEBIO project (Advanced Techniques for Biomedical Diagnostics) CZ.02.01.01/00/23_020/0008535
6 · The paper itself

Abstract

Deep eutectic solvents (DES) are used as mobile phase and stationary phase modifiers, or as for the stationary phase itself for thin layer/liquid/supercritical chromatography. Their specific properties can improve the separation selectivity, reduce peak tailing, and shorten the separation time. In terms of environmental impact, the advantages of DES are based on their biodegradability, recyclability, and stability in terms of mechanical/chemical/thermal properties. The disadvantages are related to higher viscosity and degradation in aqueous solutions. This review focuses on works that have been published since 2019, the year the excellent comprehensive review by Cai and Qiu was printed. Selected parameters are discussed that should be considered when DES are preferred over commonly used mobile and stationary phases due to green chemistry trends, while taking into account their limitations in modern LC separations. This review also centres on critical aspects of DES applications in the field of liquid and supercritical fluid chromatographic separations.

Indexed as

deep eutectic solventsgreen chemistryliquid chromatographymobile phase additiveseparation efficiencystationary phase modification

Identifiers

PMID40329693
PMCPMC12056473

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.