Evidence map›Paper›PMID 40329630›Full record

ArticleInsect science2026

fmd/fmd2/DHX16-dsx cascade in sex determination of one Hemiptera species, Laodelphax striatellus.

Youyuan Chen, Zeping Mao, Yangwei Gao, Haiqiang Wang, Jinjun Ying, Lin Wang, Xinghua Wang, Shan Xiao, Jianghua Chen, Junmin Li and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insect science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Youyuan ChenState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.ORCID https://orcid.org/0000-0002-8385-8912
Zeping MaoState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Yangwei GaoState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Haiqiang WangState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Jinjun YingState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Lin WangState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Xinghua WangState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Shan XiaoNingbo Academy of Agricultural Sciences/Ningbo Key Laboratory of Testing and Control for Characteristic Agro-Product Quality and Safety, Ningbo, Zhejiang Province, China.
Jianghua ChenNingbo Academy of Agricultural Sciences/Ningbo Key Laboratory of Testing and Control for Characteristic Agro-Product Quality and Safety, Ningbo, Zhejiang Province, China.
Junmin LiState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.
Chuanxi ZhangState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.ORCID https://orcid.org/0000-0002-7784-1188
Jichong ZhuoState Key Laboratory of Agricultural Products Safety, Key Laboratory of Biotechnology in Plant Protection of MARA and Institute of Plant Virology, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant Virology, Ningbo University, Ningbo, Zhejiang Province, China.ORCID https://orcid.org/0000-0001-9956-8621

Funding

Key Projects of Ningbo Natural Science FoundationNational Key Research and Development Plan in the 14th five year planNational Natural Science Foundation of China 32230086National Natural Science Foundation of China 32372516National Natural Science Foundation of China U23A6006Ningbo Public Welfare Science and Technology Plan Project
6 · The paper itself

Abstract

Although recent investigations have identified a novel regulatory cascade involving female determiner (fmd), female determiner 2 (fmd2), and doublesex (dsx) in Hemiptera species, the evolutionary conservation and molecular mechanisms governing the fmd/fmd2-dsx pathway remain poorly characterized. The small brown planthopper, Laodelphax striatellus (Hemiptera: Delphacidae), represents an ideal model system for elucidating the evolutionary dynamics of sex determination pathways, as its underlying mechanism remains undefined. Here, we demonstrate that the fmd2 homolog (Lsfmd2) in L. striatellus is functionally involved in sex determination through a specific splicing isoform, LsFMD2

Indexed as

HemipteraInsect ProteinsSex Determination ProcessesAmino Acid SequenceAnimalsFemaleMaleInsect ProteinsDHX16fmd/fmd2‐dsxHemiptera speciesLaodelphax striatellussex determination pathway

Identifiers

PMID40329630
PMCPMC13441028

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.