Evidence map›Paper›PMID 40329410›Full record

ArticleJournal of health, population, and nutrition2025

The effect of antenatal care on low birth weight and neonatal mortality: protocol for umbrella review of meta-analysis.

Fentahun Alemnew Chekole, Azimeraw Arega Tesfu, Fentahun Yenealem Beyene, Wondu Feyisa Balcha

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fentahun Alemnew ChekoleDepartment of Midwifery, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia. fentahun746@gmail.com.ORCID 0000-0002-3804-2607
Azimeraw Arega TesfuDepartment of Midwifery, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Fentahun Yenealem BeyeneDepartment of Midwifery, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Wondu Feyisa BalchaDepartment of Midwifery, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World Health Organization defines low birth weight as a birth weight of less than 2500 g, regardless of the gestational age. It is regarded as the most significant predictor of infant mortality overall, particularly for deaths that occur in the first few months of life. Among all the months of a person's existence, the neonatal period, the first month of life, has one of the highest death rates. The necessity for an umbrella review is highlighted by the lack of a comprehensive synthesis of collective meta-analytic evidence connecting antenatal care as a factor of low birth weight and newborn death. Thus, this umbrella review's main goal is to thoroughly synthesize the existing meta-analytic evidence, with a focus on assessing the relationship between antenatal care with low birth weight and neonatal mortality.

methodsAll English-language meta-analyses of cohort, case-control, and cross-sectional studies that looked at the relationship between antenatal care with low birth weight and neonatal mortality will be included, regardless of the time and location of publication. To find pertinent literature for review, major medical electronic databases including Embase, CINAHL, Cochrane database, and PubMed will be used. Two reviewers will screen the eligible articles, extract data, and evaluate their quality independently. The reviewers will work together to reach a consensus on any disagreements. If there are still issues, a third reviewer will be consulted in order to fix them. The meta-umbrella R package will be used for all statistical analysis. The random-effects model and 95% prediction interval for the summary estimate will be used for both outcomes. Q and I DISCUSSION: This is the first comprehensive analysis of the effect of antenatal care on low birth weight and neonatal mortality that we are aware of. For clinicians and researchers seeking to lower low birth weight and neonatal mortality, summarizing this evidence is helpful.

trial registrationPROSPERO-CRD42024567150.

Indexed as

Infant, Low Birth WeightInfant MortalityPrenatal CareFemaleHumansInfantInfant, NewbornMeta-Analysis as TopicPregnancyResearch DesignSystematic Reviews as TopicAntenatal careLow birth weightMeta-analysesNeonatal mortality

Identifiers

PMID40329410
PMCPMC12057056

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.