ArticleBMC research notes2025
Impact of malnutrition and associated factors on rifampicin/multi-drug-resistant tuberculosis treatment outcomes among patients treated in alert and St. Peter's Specialized Hospitals, Addis Ababa, Ethiopia: a retrospective follow-up study.
Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Development and validation of a LASSO-derived nomogram for predicting unfavorable treatment outcomes in drug-resistant pulmonary tuberculosis.BMC infectious diseases · 2026Article
- Evaluating treatment outcomes stratified by regimen among drug-resistant TB patients in Sierra Leone.Public health action · 2026Article
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Authors and funding
5 authors.
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Abstract
objectiveThis study was aimed to assess the impact of malnutrition and associated factors on rifampicin/multi-drug-resistant tuberculosis treatment outcomes among patients treated in Alert and St. Peter's Specialized Hospitals, Addis Ababa, Ethiopia.
resultsOur study included 344 RR/MDR-TB patients, of which 43.3% were undernourished. The overall unsuccessful treatment outcome was 22.1% (95% CI 0.18, 0.27). Patients with undernutrition were over eight times more likely to develop unsuccessful treatment outcomes [AOR = 8.32 (95% CI 4.48, 15.46)] compared to normal/ overweight individuals. After we computed the binary logistic regression analysis separately for patients with undernutrition and normal/ overweight nutritional status, age, residence, occupation, chest x-ray, anemia, co-morbidities, cigarette smoking, and alcohol drinking were significantly associated with unsuccessful treatment outcomes among undernourished patients, while age, HIV, and smoking were significantly associated with unsuccessful treatment outcomes among patients with normal/overweight individuals.
conclusionsIn this study, undernutrition had a remarkable impact on unsuccessful treatment outcomes. Therefore, further researches need to be conducted to integrate the management of undernutrition with the DR-TB treatment program.
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