Evidence map›Paper›PMID 40329220›Full record

ArticleBMC microbiology2025

Genomic and phenotypic insights into ST164 bla

Kun Wang, Weidong Zhu, Lu Gong, Xiaolu Yang, Haowei Ye, Zhenghao Lou, Jie Yang, Xiawei Jiang, Wei Li, Fangfang Tao and 3 more

Abstract read
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Comparative genomic insights into carbapenem-resistant versus susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
  4. Review
  5. Carbapenem-ResistantMicroorganisms · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kun Wang *School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Weidong Zhu *Department of Emergency Medicine, Traditional Chinese Medical Hospital of Zhuji, Zhuji, China.
Lu GongSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Xiaolu YangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Haowei YeCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhenghao LouCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jie YangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Xiawei JiangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Wei LiSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Fangfang TaoSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China.
Hao XuCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Beiwen ZhengSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. zhengbw@zju.edu.cn.
Wenhong LiuSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. lwh@zcmu.edu.cn.

Funding

Fundamental Research Funds for the Central Universities 2022ZFJH003National Key Research and Development Program of China 2023YFC2308400National Natural Science Foundation of China 82072314
6 · The paper itself

Abstract

backgroundCarbapenem-resistant Acinetobacter baumannii (CRAB) poses a critical global threat, especially in ICUs. Yet, reports on ST164 CRAB harboring bla

methodsBacterial identification was performed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) mass spectrometry. Antimicrobial susceptibility was assessed via agar and broth microdilution. Whole-genome sequencing employed Illumina NovaSeq 6000 and Oxford Nanopore platforms. Resistance genes, insertion elements, transposons, and integrons were detected using ResFinder, PlasmidFinder, VFDB, ISFinder, pdifFinder, and IntegronFinder. Strains were typed by MLST, and a phylogenetic tree was constructed with kSNP3.0. Genetic environment diagrams were generated using Easyfig 2.2.5.

resultsTwo bla

conclusionThis study provides the genomic and phenotypic characterization of intestinally colonized ST164 bla

Indexed as

Acinetobacter baumanniiAcinetobacter Infectionsbeta-LactamasesIntestinesAnimalsAnti-Bacterial AgentsCarbapenemsChinaDrug Resistance, Multiple, BacterialGenome, BacterialGenomicsHumansMiceMicrobial Sensitivity TestsMultilocus Sequence TypingPhenotypeAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesCarbapenemsAntibiotic resistancebla NDM-1CRABIntestinal colonizationWhole-genome sequencing

Identifiers

PMID40329220
PMCPMC12057158

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.