ArticleThe journal of headache and pain2025
The burden of migraine and predictions in the Asia-Pacific region, 1990-2021: a comparative analysis of China, South Korea, Japan, and Australia.
Article in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Migraine is a risk factor for dementia: a systematic review and meta-analysis of cohort studies.The journal of headache and pain · 2025Pooled it
- Driving Mechanisms and Future Trends of Migraine and Tension-Type Headache Burden in G20 Countries: A Comparative Analysis Utilizing Decomposition Analysis and Explainable Machine Learning.Pain and therapy · 2026Article
- Burden and trends of decubitus ulcers in East Asia, 1990-2021, with projections to 2031: a comprehensive analysis of the global burden of disease study.Journal of health, population, and nutrition · 2026Article
- The Impact of Intelligent Medical Systems Combined with Interdisciplinary Care Teams in Home-Based Care Services for Disabled Elderly Individuals: A Prospective Intervention Study.Journal of multidisciplinary healthcare · 2026Article
- Trends in the Disease Burden of Migraine Among Women of Reproductive Age (15-49 Years) in Low- and Middle-Income Countries, 1990-2023.International journal of women's health · 2026Article
- Migraine Disease Burden and Trends (1990-2021): A Multidimensional Comparative Analysis of China and Other G20 Countries.Brain and behavior · 2025Article
- Analysis and comparison of the trends in the burden of migraine in China and globally from 1990 to 2021, with a forecast to 2031.Frontiers in neurology · 2025Article
- Trends and comparative analysis of the burden of migraine in China and globally from 1990 to 2021: an analysis based on the 2021 global burden of disease study.Frontiers in neurology · 2025Article
- Long-term trends and future projections of the burden of diabetic nephropathy in China: a comprehensive analysis of GBD data from 1990 to 2036.Frontiers in endocrinology · 2025Article
- Delphi consensus on the real-world application of the updated diagnostic and treatment guidelines for migraine in Asia Pacific.Frontiers in neurologyArticle
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Authors and funding
7 authors.
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Abstract
backgroundMigraine is a leading cause of disability worldwide, significantly impacting quality of life and healthcare systems. Despite its high prevalence and burden, migraine remains underprioritized in global health policies. This study examines the epidemiological trends of migraine in Australia, China, Japan, and South Korea from 1990 to 2021, highlighting regional disparities and forecasting future burdens.
methodsThis study utilized data from the Global Burden of Disease (GBD) 2021 to analyze incidence, prevalence, and years lived with disability (YLDs) of migraine. Age-standardized rates (ASRs) were calculated to enable fair cross-country comparisons. Joinpoint regression analysis was applied to assess temporal trends, while Bayesian age-period-cohort (BAPC) modeling was used to project future trends until 2050. Additionally, decomposition analysis was conducted to differentiate the effects of population aging, growth, and epidemiological changes.
resultsIn 2021, China had the highest migraine burden, with 13.05 million new cases and 184.75 million prevalent cases, followed by Australia, Japan, and South Korea. Incidence rates peaked in adolescence (10-14 years), while prevalence and disability were highest in middle-aged women (40-44 years). From 1990 to 2021, Australia exhibited stable trends, China experienced increasing burden, Japan saw a decline due to aging, and Korea exhibited mixed patterns influenced by opposing demographic and epidemiological forces. Future projections suggest a stable trend in Australia, declining incidence in China and Japan, and continued burden in Korea.
conclusionMigraine remains a significant public health challenge across all four countries, with age, gender, and demographic changes playing key roles in burden variations. The study highlights the need for region-specific healthcare strategies and age- and gender-sensitive interventions. Future research should explore socioeconomic, behavioral, and healthcare access factors to refine migraine management strategies.
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