ArticleNature materials2025
Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury.
Article in Nature materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The trial behind it
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Who cites it
53 citing papers in PubMed.
- Ultrasound-activated piezoelectric patch enhances mitophagy and synergistic anti-inflammation to promote neurological repair after TBI.Bioactive materials · 2027Article
- Nanozyme-based therapeutic strategies for traumatic brain injury.International journal of pharmaceutics: X · 2026Review
- Ultrasonic-driven force-electric nanodomains orchestrate lysosome-to-mitochondria functional cascade to accelerate bone regeneration.Bioactive materials · 2026Article
- Tissue engineering for traumatic spinal cord injury: Research advances and clinical translation.Bioactive materials · 2026Review
- Intratumoral therapeutic dust for chemo-photodynamic combination treatment.Science advances · 2026Article
- A cell motility-based selective hydrogel enables rapid generation of nerve-repairing blood clots.Bioactive materials · 2026Article
- Review
- Post-Translational Modifications in Traumatic Brain Injury: Decoding the Proteomic Landscape and Molecular Mechanisms of Secondary Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Rewiring of NestinNeuroscience bulletin · 2026Article
- A biodegradable piezoelectric vertebral implant for programmable electro-neuromodulation in spinal cord injury.Science advances · 2026Article
- A Millimeter-Scale Implantable Magneto-Mechano-Electric Transducer Based on BTO Piezoelectric Ceramics for Remote Wireless Electrical Stimulation of Injured Sciatic Nerves.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Electrical Signals at the Subcellular Scale: How Electroactive Materials Regulate Stem Cell Fate.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Defect-Mediated Sonodynamic Catalysis on Calcium-Deficient Hydroxyapatite Nanoparticles Coordinating Bacterial Elimination and Bone Regeneration against Osteomyelitis.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Stimuli-Responsive Piezoelectric Scaffold as an AdvancedACS omega · 2026Article
- NIR-II Fluorescent Nanoplatforms with Defect-Regulated Piezoelectricity for Dual NIR-II/MRI-Guided, Hypoxia-Resilient Piezo-Chemodynamic Therapy and cGAS-STING Activation in Orthotopic Liver Tumor.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Self-assembled biomimetic nanocomposite integrating defect-enhanced piezoelectricity with NIR-II fluorescence and MR imaging for ultrasound-triggered piezo/chemodynamic therapy of subcutaneous glioma.Journal of nanobiotechnology · 2026Article
- Neuron-targeting piezoelectric microneedles disrupt pro-tumorigenic neuron-immune crosstalk and restore anti-tumor immunity in melanoma.Nature communications · 2026Article
- Integrated cryopreservation-thawing-transplantation platform for neural stem cell-based spinal cord injury repair.Bioactive materials · 2026Article
- Accelerated diabetic wound healing via microenvironmental modulation treated by hydrogel encapsulated with neural stem cells.Regenerative therapy · 2026Article
- Graphdiyne-Ivy fiber neural scaffold promotes stem cell directed differentiation and neuronal maturation.Materials today. Bio · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Traumatic brain injury (TBI) is associated with life-threatening and permanent disabilities. Given the limited capacity of neurons to regenerate, effective treatments for TBI are lacking. Neural stem cells (NSCs) can differentiate into fully functioning neurons and thus hold promise for TBI treatment. Nonetheless, NSC differentiation and proliferation are slow and inefficient. Studies have shown that piezoelectric stimulation is capable of promoting the differentiation and proliferation of NSCs. Here, we describe barium titanate-reduced graphene oxide (BTO/rGO) hybrid piezoelectric nanostickers that promote NSC proliferation and differentiation. These hybrid nanostickers attach to NSC membranes, serving as long-term generators of piezoelectric potentials upon ultrasound stimulation. BTO/rGO nanostickers promote rapid neuronal differentiation and maturation by activating the voltage-gated calcium channel/Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.