Evidence map›Paper›PMID 40329024›Full record

ArticleJournal of exposure science & environmental epidemiology2026

Air pollution and preterm birth: comparing trimester average and repeated threshold exposure metrics in a North Carolina birth cohort, 2003-2015.

Sanjida J Mowla, Alison K Krajewski, Adrien A Wilkie, Kristen M Rappazzo, Thomas J Luben

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Article in Journal of exposure science & environmental epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sanjida J MowlaOak Ridge Institute of Science and Education (ORISE) Research Participant at the United States Environmental Protection Agency, Research Triangle Park, NC, USA.
Alison K KrajewskiUnited States Environmental Protection Agency, Office of Research and Development, Center for Public Health & Environmental Assessment, Research Triangle Park, NC, USA.
Adrien A WilkieUnited States Environmental Protection Agency, Office of Research and Development, Center for Public Health & Environmental Assessment, Research Triangle Park, NC, USA.
Kristen M RappazzoUnited States Environmental Protection Agency, Office of Research and Development, Center for Public Health & Environmental Assessment, Research Triangle Park, NC, USA.
Thomas J LubenUnited States Environmental Protection Agency, Office of Research and Development, Center for Public Health & Environmental Assessment, Research Triangle Park, NC, USA. luben.tom@epa.gov.ORCID http://orcid.org/0000-0002-7867-5126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposures to ambient air pollutants during pregnancy are associated with preterm birth (PTB) in studies that evaluate average pollutant concentrations during potential "windows of susceptibility," referred to as critical windows.

objectiveWe evaluated associations between ozone (O

methodsWe analyzed data from North Carolina (NC) birth certificates from the NC Birth Defects Monitoring Program, limited to live, singleton births without birth defects and delivered from 2003-2015. The EPA's Fused Air Quality Surface Using Downscaling (fCMAQ) model was used to assign exposures for trimester-average and daily threshold exceedances for O

resultsAmong the cohort of 1,368,370 births, 8.4% were PTBs. The number of daily exposure exceedances ranged from 0 to 81 days over different threshold concentrations during trimester 1 or 2. There was slight to moderate agreement in risk associated with trimester average and daily threshold exposures exceedances, with decreased agreement among higher threshold concentrations. RDs ranged from -31 to 29 for average O SIGNIFICANCE: This study provides insights into the heterogeneity in risk of PTB when assessing different air pollution exposure metrics. IMPACT: This study investigates the impact of O

Indexed as

Air PollutantsAir PollutionMaternal ExposureParticulate MatterPremature BirthAdultBirth CohortCohort StudiesFemaleHumansInfant, NewbornNorth CarolinaOzonePregnancyPregnancy TrimestersAir PollutantsOzoneParticulate MatterExposure metricsFine particulate matterOzonePreterm birthRepeated exposures

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.