ReviewNature reviews. Cardiology2025
Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity.
Review in Nature reviews. Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Testing effects of paced breathing on plasma Aβ and brain perivascular spaces.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2026Trial
- Identifying stress-relevant events in everyday nursing practice using psychophysiological outcomes - an observational multimethod study.BMC nursing · 2026Article
- Utility and best practices for clinical diagnostic testing of the autonomic nervous system: A Consensus Statement Endorsed by the American Autonomic Society and the American Association of Neuromuscular & Electrodiagnostic Medicine.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Review
- EHR perception and momentary well-being in oncology professionals.ESMO real world data and digital oncology · 2026Article
- Autonomic and limbic system functioning, early life stress, and depressive symptoms in adolescence.Neurobiology of stress · 2026Article
- Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026Review
- Experience-dependent development of vagal circuitry in rodents and humans.Neuroscience and biobehavioral reviews · 2026Review
- Renal denervation in experimental autoimmune myocarditis: association with cardiac function and changes in calcium and MAPK/ERK signaling.Basic research in cardiology · 2026Article
- Portable Breathing Monitoring With Phase-Resolved Airflow Dynamics Enabled by a Dual-Response Flexible PZT Sensor.Advanced healthcare materials · 2026Article
- Free-living associations between resting heart rate parameters and cardiometabolic health in adults.Physiological reports · 2026Article
- Stress reactivity of the autonomic nervous system in youth with and without major depressive disorder.European child & adolescent psychiatry · 2026Article
- Beyond Single-Lead ECG-Derived Respiration Analysis: Use of Vectorcardiograms from the EASI-System for Breathing Frequency Estimation-A Feasibility Study.Sensors (Basel, Switzerland) · 2026Article
- Daily Stress and Heart Rate Variability Among Mindfulness Meditation Practitioners: mHealth Observational Study.Journal of medical Internet research · 2026Observational
- Respiration as a dynamic modulator of sensory sampling.Nature communications · 2026Article
- Daily Paced Breathing Sessions Induce Left Orbitofrontal Volume Changes Linked to Cognitive Outcomes.medRxiv : the preprint server for health sciences · 2026Article
- Disentangling Respiratory Phase-Dependent and Phase-Independent Components of Anticipatory Cardiac Deceleration.Psychophysiology · 2026Article
- Heart-Brain Temporal Coupling as a Candidate Biomarker of Self-Congruency.Biomedicines · 2026Article
- Why The Polyvagal Theory Is Untenable: An international expert evaluation of the polyvagal theory and commentary upon Porges, S.W. (2025). Polyvagal theory: current status, clinical applications, and future directions. Clin. Neuropsychiatry, 22(3), 169-184.Clinical neuropsychiatry · 2026Article
- Addressing Hypertension Treatment Disparities Via Renal Denervation.Current hypertension reports · 2026Review
- Modulation of autonomic responses to cognitive tasks under acute mental stress.Scientific reports · 2026Article
Corrections and comments
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Authors and funding
29 authors.
Funding
Abstract
The variation of heart rate in phase with breathing, known as 'respiratory sinus arrhythmia' (RSA), is a physiological phenomenon present in all air-breathing vertebrates. RSA arises from the interaction of several physiological mechanisms but is primarily mediated by rhythmic changes in cardiac parasympathetic (vagal) activity, increasing heart rate during inspiration and decreasing heart rate during expiration. RSA amplitude is an indicator of autonomic and cardiac health; RSA is diminished or absent in common pathological conditions such as chronic heart failure and hypertension. In this Expert Recommendation, we argue that the term 'RSA', although historically important, is semantically inaccurate and carries misleading pathological connotations, contributing to misunderstanding and misinterpretation of the origin and the physiological importance of the phenomenon. We propose replacing 'RSA' with the term 'respiratory heart rate variability' (RespHRV), which avoids pathological connotations and emphasizes the specific respiratory contribution to heart rate variability. We clarify that RespHRV encompasses respiratory-related heart rate variations in both the low-frequency and high-frequency bands traditionally defined in heart rate variability analysis, and that its amplitude should not be misconstrued as a measure of vagal tone. Adopting the proposed term 'RespHRV' is expected to unify understanding and stimulate further experimental and clinical research into the physiological mechanisms and functional importance of this phenomenon.
Indexed as
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40328963What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.