ArticleEye (London, England)2025
Diabetic foveal neovascularization is associated with diminished subfoveal choroidal flow on optical coherence tomography angiography.
Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate the role of retinal and choriocapillaris blood flow in the development of diabetic foveal neovascularization (DFN) using optical coherence tomography angiography (OCTA).
methodsEyes with proliferative diabetic retinopathy (PDR) and DFN underwent OCTA imaging; defined as surface retinal neovascularization within the central foveal 1 mm diameter circle. 3 × 3 and 6 × 6 mm
results18 eyes of 18 patients were included in each of the 3 groups: healthy controls, PDR with and without DFN. Choriocapillaris AFI was significantly lower in PDR with DFN than healthy controls in all but the 6 × 6 mm
conclusionsOur findings suggest that choroidal hypoperfusion may be a potential driving factor for the development of DFN. The detection of these changes in the smaller scans of the total and subfoveal areas suggests a rather exaggerated and localized subfoveal distribution of ischaemia. Larger longitudinal studies are needed to explore the use of subfoveal choroidal AFI as a prognostic sign for DFN.
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