ArticleScientific reports2025
Influence of biopolymer based gold nanoparticles and photobiomodulation in in vitro wound healing.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Antimicrobial effects of repeated 405 nm low-level-laser photobiomodulation: an In-vitro study on surgical wound pathogens.Lasers in medical science · 2026Article
- Photobiomodulation stimulates mitochondrial function and cell proliferation in meniscus-derived stem cells (MeSCs) via activation of TRPV1 channel.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In nanomedicine, gold nanoparticles (GNPs) are based on metal-based nanomaterials and have attracted considerable attention from researchers for their use in drug delivery, including wound healing. This study examined the use of Gum tragacanth (GT) for producing gold nanoparticles (GNPs) through the green synthesis method (GT-GNPs). The antibacterial activity of GT-GNPs against pathogenic bacterial strains, as well as assess the wound healing potential of GT-GNPs combined with photobiomodulation (PBM) on normal and diabetic wound models (in vitro). In physicochemical characterization results, we found that the synthesized nanoparticles are 10-20 nm with an average of 12 ± 2 nm in size, and smooth surface and confirmed the presence of GT on the GT-GNPs. It also possessed optimal antibacterial activity and was confirmed through flow cytometry studies. Furthermore, we examined the combined effect of GT-GNPs and PBM against normal and diabetic wound models in WS1 (Humal Fibroblast cells), including cell morphology, percentage of wound closure, nuclear, and filamentous (F)-actin morphology. The combined effects of GT-GNPs and PBM effectively achieved progressive wound closure. In summary, this study has demonstrated that treating GT-GNPs has no adverse effects on both normal and diabetic wound healing processes.
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Registered trials
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