Evidence map›Paper›PMID 40328734›Full record

ArticleNPJ breast cancer2025

Breastfeeding attributable fraction of triple negative breast cancer in the US.

Rachel Jaber Chehayeb, Nicole Odzer, Roberta A Albany, Leah Ferrucci, Daniel Sarpong, Rafael Perez-Escamilla, Jessica B Lewis, Amanda I Phipps, Allison Meisner, Lajos Pusztai

Abstract read
In one paragraph

Article in NPJ breast cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. RISE UP for breast cancer 2024: conference highlights & takeaways.Breast cancer research and treatment · 2026
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel Jaber ChehayebYale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-2117-7433
Nicole OdzerYale University School of Medicine, New Haven, CT, USA.
Roberta A AlbanyCancer-in-the-Know, Mt Penn, PA, USA.
Leah FerrucciYale School of Public Health, New Haven, CT, USA.
Daniel SarpongDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Rafael Perez-EscamillaYale School of Public Health, New Haven, CT, USA.
Jessica B LewisDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Amanda I PhippsDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
Allison MeisnerPublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Lajos PusztaiYale University School of Medicine, New Haven, CT, USA. lajos.pusztai@yale.edu.ORCID http://orcid.org/0000-0001-9632-6686

Funding

Short Term Research Training: Students in Health Professional SchoolsT35DK104689 · NIDDK · YALE UNIVERSITY · PI LLOYD G CANTLEY, Sarwat I Chaudhry · 2015 to 2026
$2.6M
NIDDK NIH HHS T35 DK104689
6 · The paper itself

Abstract

Rates of triple negative breast cancer (TNBC) are higher in Black women than in non-Hispanic White women. Breastfeeding duration and younger age at first birth are known risk factors for TNBC and vary by race. To quantify the contribution of these risk factors to disparities in TNBC, we calculated the population-attributable fraction (PAF). A PubMed search was performed to identify relevant studies and pooled odds ratios for breastfeeding for < 6 months and age at first birth < 25 years were calculated. PAF was calculated using the Levin formula. PAF of breastfeeding for < 6 months was 12% (95% confidence interval (CI) 5-20%) among White women and 15% (95%CI 3-26%) among Black women. We estimate that up to 15% of annual new TNBC in Black women and 12% in White women might be avoided by supporting breastfeeding. Policies supporting breastfeeding could hence reduce TNBC incidence and lessen racial disparities.

Identifiers

PMID40328734
PMCPMC12055980

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.