Evidence map›Paper›PMID 40328372›Full record

ArticleJournal of substance use and addiction treatment2025

Relationship between opioid use disorder during pregnancy, delivery-related outcomes, and healthcare utilization in Michigan Medicaid, 2012-2021.

Clayton J Shuman, Xiaosong Zhang, Stephanie V Hall, Anca Tilea, Sarah J Clark, Ashlee J Vance, Anna Courant, Kara Zivin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Clayton J ShumanDepartment of Systems, Populations and Leadership, University of Michigan School of Nursing, Ann Arbor, MI, USA; Program on Women's Healthcare Effectiveness Research, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA; Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, MI, USA; VA Ann Arbor Healthcare System, Ann Arbor, MI, USA; Center for the Study of Drugs, Alcohol, Smoking, and Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: clayshu@med.umich.edu.
Xiaosong ZhangDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. Electronic address: xiaosonz@umich.edu.
Stephanie V HallDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA; Program on Women's Healthcare Effectiveness Research, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: stephall@umich.edu.
Anca TileaDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. Electronic address: atilea@umich.edu.
Sarah J ClarkChild Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI, USA. Electronic address: saclark@umich.edu.
Ashlee J VanceCenter for Health Policy and Health Services Research, Henry Ford Health System, Detroit, MI, USA. Electronic address: avance2@hfhs.org.
Anna CourantDepartment of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: annavp@umich.edu.
Kara ZivinDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA; Program on Women's Healthcare Effectiveness Research, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA; Department of Health Policy and Management, University of Michigan School of Public Health, Ann Arbor, MI, USA; VA Ann Arbor Healthcare System, Ann Arbor, MI, USA. Electronic address: kzivin@umich.edu.

Funding

Mom is medicine: Implementing maternal-delivered nonpharmacologic care for neonatal opioid withdrawalK08HD105986 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Clayton John Shuman · 2022 to 2026
$818k
HSRD VA IK6 HX003397NICHD NIH HHS K08 HD105986
6 · The paper itself

Abstract

introductionPregnant individuals with opioid use disorder (OUD) deliver >20,000 infants annually in the United States, with serious health consequences for perinatal individuals and their infants. This study compares delivery-related outcomes and healthcare utilization among Michigan Medicaid-enrolled perinatal individuals with and without an OUD diagnosis.

methodsWe conducted a retrospective cohort study among Michigan Medicaid enrollees aged 15-44 who delivered a live infant between 2012 and 2021.

resultsThe cohort included 218,890 deliveries among 170,002 individuals enrolled continuously in Michigan Medicaid for nine months before delivery and up to three months postpartum. Of those, 3.26 % had an OUD diagnosis during this analytic period. Perinatal individuals with OUD identified primarily as White (82.9 %), lived in urban areas (77.2 %), and had a lower income (68.6 %). Among individuals with OUD, 31 % had another behavioral health diagnosis and 55.1 % received a prescription for a psychotropic medication. Of those with OUD, 47.4 % received a prescription for medication for OUD. Deliveries with OUD versus without OUD had a lower probability of cesarean delivery (aOR = 0.89) but higher odds of preterm delivery (aOR = 1.31). Those with OUD had higher likelihood of ambulatory (aOR = 1.99), ED/observational (aOR = 1.19), psychotherapy (aOR = 5.48), and substance use disorder care (aOR = 27.05) visits than those without OUD.

conclusionsMedicaid-enrolled perinatal individuals in Michigan with OUD had higher rates of preterm birth and healthcare utilization compared to those without OUD. Clinicians and policymakers should target early detection and tailored, coordinated treatment to better address the needs of these individuals.

Indexed as

MedicaidOpioid-Related DisordersPatient Acceptance of Health CarePregnancy ComplicationsAdolescentAdultCesarean SectionFemaleHumansInfant, NewbornMichiganPregnancyPregnancy OutcomePremature BirthRetrospective StudiesUnited StatesHealthcare utilizationMedicaidOpioid use disorderPerinatal behavioral healthPerinatal mental healthPreterm birth

Identifiers

PMID40328372
PMCPMC12163692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.