Evidence map›Paper›PMID 40327914›Full record

ArticleInternational journal of surgery case reports2025

Squamous cell carcinoma arising from mature cystic teratoma of the ovary in a premenopausal women: A rare case report.

Nigat Amsalu Addis, Kinfemicheal Tilahun Yigzaw, Bewketu Abebe Alemu, Kassa Berie Zegeye, Eyoel Negash Taddesse, Getachew Shiferaw Yigezaw

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nigat Amsalu AddisDepartment of Obstetrics and Gynecology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. Electronic address: nigat.amsalu@uog.edu.et.
Kinfemicheal Tilahun YigzawSchool of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia. Electronic address: yigzawkinfe@gmail.com.
Bewketu Abebe AlemuDepartment of Pathology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Kassa Berie ZegeyeDepartment of Pathology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Eyoel Negash TaddesseDepartment of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Getachew Shiferaw YigezawDepartment of Obstetrics and Gynecology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMature cystic teratoma (MCT) is the most common type of ovarian germ cell tumour, with a rare complication of malignant transformation, often presenting as squamous cell carcinoma (SCC). Early detection is critical for improving outcomes, especially in younger patients. CASE PRESENTATION: A 25-year-old para-2 female presented with a 6-month history of dull abdominal pain, swelling, appetite loss, and weight loss. Examination revealed a firm abdominopelvic mass, and ultrasound indicated a 15 × 12 cm adnexal mass. Staging laparotomy revealed a 20 × 15 cm left ovarian mass with ascitic fluid and enlarged para-aortic lymph nodes. Histopathological analysis confirmed keratinizing poorly differentiated SCC arising from MCT. DISCUSSION: This case highlights the rarity of malignant transformation in MCTs, particularly in younger women. The absence of distinct symptoms and reliance on imaging necessitates a high index of suspicion for malignancy when evaluating ovarian masses.

conclusionThe patient underwent successful staging and surgery, followed by an initial chemotherapy regimen. However, she lost follow-up, emphasizing the challenge of maintaining care continuity in remote areas. Close monitoring and education regarding the importance of follow-up care are crucial for improving outcomes in such cases.

Indexed as

Case reportsMature cystic teratomaOvaryPremenopausalSquamous cell carcinoma

Identifiers

PMID40327914
PMCPMC12124637

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