ArticlePloS one2025
Hematological changes in the blood of experimental male and female albino rats on exposure to pesticide, dimethoate.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEvaluating pesticides' impacts on human health, ecological balance, and agricultural production is the main focus of research on pesticides. The present study aims to investigate the hematological parameters of both genders of albino rats after exposure to dimethoate pesticides. MATERIAL AND
methodsThere was a total of eight groups of albino rats, there were two control groups, and treatment groups were further divided into six groups. A low dose of: 5ml was given to the T1 group, a medium dose of 10ml was given to the T2 group, and a high dose of 20 ml was given to the T3 group. Each group contained nine rats in them (n=9). The first two groups of albino rats were taken as the control group and placed in normal conditions. The other six groups of albino rats were administered sub-lethal doses of dimethoate pesticide by mixing this pesticide in food by oral gavage for 90 days.
resultsThe study showed that the number of white blood cells, platelets count, granulocyte count and lymphocyte count in both genders of albino rats after 30-, 60- and 90-days exposure to dimethoate was significantly increased where simultaneously the number of red blood cells, hemoglobin level, mean corpuscle hemoglobin count, and mean corpuscle hemoglobin concentration count was decreased considerably due to exposure of dimethoate pesticide in both genders of albino rats. No changes observed in the control group of male and female albino rats. This study concluded that dimethoate pesticide effects the blood parameter of male and female albino rats.
conclusionThe study's findings highlight the importance of strict regulatory policies and thorough risk assessment techniques in order to reduce the harmful impacts of pesticides on the health of people and the environment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.