Evidence map›Paper›PMID 40327613›Full record

ArticleACS biomaterials science & engineering2025

Development of Pd-Loaded Hf-Based Metal-Organic Framework as a Dual-Modal Contrast Agent for Photoacoustic Imaging and Computed Tomography.

Yen-Chang Chen, Yu-Sheng Yu, Yu-Kang Wang, R K Rakesh Kumar, Cho-Yin Lee, Cheng-Hsin Chuang, Lun-De Liao, Kevin C-W Wu

Abstract read
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In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yen-Chang ChenDepartment of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan.
Yu-Sheng YuDepartment of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0002-8806-517X
Yu-Kang WangDepartment of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan.
R K Rakesh KumarInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli 350401, Taiwan.ORCID 0000-0001-7312-4512
Cho-Yin LeeDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei 30010, Taiwan.
Cheng-Hsin ChuangInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.ORCID 0000-0001-9097-1377
Lun-De LiaoInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli 350401, Taiwan.
Kevin C-W WuInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Miaoli 350401, Taiwan.ORCID 0000-0003-0590-1396

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive cancer imaging significantly improves diagnostics by providing comprehensive structural and functional information about tumors. Herein, we explored palladium nanoparticles loaded hafnium-based metal-organic framework (MOF) (Hf-EDB), i.e., Pd@Hf-EDB as an efficient dual modal contrast agent for computed tomography (CT) and photoacoustic imaging (PAI). The synergistic collaborations between (i) high-Z element Hf-based MOF with superior X-rays absorbing capabilities, (ii) H

Indexed as

Contrast MediaMetal-Organic FrameworksPalladiumPhotoacoustic TechniquesTomography, X-Ray ComputedAnimalsCell Line, TumorHumansMetal NanoparticlesMiceMice, NudeContrast MediaMetal-Organic FrameworksPalladiumcontrast agentCT/PA dual-modal imagingmetal−organic frameworkpalladium nanoparticles

Identifiers

PMID40327613
PMCPMC12152835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.