Evidence map›Paper›PMID 40327282›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025

Cobalt oxide modified screen-printed carbon electrode for electrochemical detection of high blood pressure treating drug: reserpine.

Chenxi Wu, Shengzhou Qiu, Sima Akter, Shaoli Hong, Huihong Liu, Sakil Mahmud

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chenxi WuCollege of Chemistry and Chemical Engineering, Hubei Key Laboratory of Biomass Fibers and Eco-Dyeing and Finishing, Wuhan Textile University, Wuhan, 430200, People's Republic of China.
Shengzhou QiuCollege of Chemistry and Chemical Engineering, Hubei Key Laboratory of Biomass Fibers and Eco-Dyeing and Finishing, Wuhan Textile University, Wuhan, 430200, People's Republic of China.
Sima AkterFaculty of Medicine, Enam Medical College and Hospital, University of Dhaka, Dhaka, 1000, People's Republic of Bangladesh.
Shaoli HongCollege of Chemistry and Chemical Engineering, Hubei Key Laboratory of Biomass Fibers and Eco-Dyeing and Finishing, Wuhan Textile University, Wuhan, 430200, People's Republic of China.
Huihong LiuCollege of Chemistry and Chemical Engineering, Hubei Key Laboratory of Biomass Fibers and Eco-Dyeing and Finishing, Wuhan Textile University, Wuhan, 430200, People's Republic of China. huihongliu@wtu.edu.cn.ORCID http://orcid.org/0000-0002-2192-8698
Sakil MahmudIvory V. Nelson Center for the Sciences, Department of Chemistry and Physics, Lincoln University, 1570 Baltimore Pike, Oxford, PA, 19352, USA. smahmud@lincoln.edu.ORCID http://orcid.org/0000-0002-2015-2824

Funding

National Natural Science Foundation of China 22204123
6 · The paper itself

Abstract

This study presents the development of a cobalt oxide-modified screen-printed carbon electrode (CoO/SPCE) for the electrochemical detection of reserpine (RES), a drug used to treat high blood pressure. The CoO/SPCE was fabricated using an optimized electrodeposition method, resulting in a sensitive and reproducible platform for RES detection. Electrochemical characterization demonstrated that the CoO/SPCE exhibited superior electrocatalytic activity, as evidenced by a notable increase in oxidation peak current compared to bare and activated SPCEs. The electrode showed a linear response to RES concentrations ranging from 2 to 100 μM with a detection limit of 1.08 μM. Additionally, the sensor demonstrated good stability and reproducibility with relative standard deviations (RSDs) of 5.11% and 2.72%, respectively. This work highlights the CoO/SPCE's potential for practical pharmaceutical analysis, offering a novel approach to enhancing the sensitivity and reliability of electrochemical sensors for drug monitoring.

Indexed as

CarbonCobaltElectrochemical TechniquesOxidesReserpineElectrodesHumansLimit of DetectionReproducibility of ResultsCarbonCobaltcobalt oxideOxidesReserpineCobalt oxide-modified electrodeElectrochemical sensorPharmaceutical analysisReserpine detectionScreen-printed carbon electrode

Identifiers

PMID40327282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.